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Fig. 4 | Acta Neuropathologica Communications

Fig. 4

From: Myelin-specific multiple sclerosis antibodies cause complement-dependent oligodendrocyte loss and demyelination

Fig. 4

MS#30 and NMO#53 have distinct effects on astrocytes and neurons. Immunostaining of astrocytes (a–f) and neurons (g–r) in the slices treated with rAbs with or without HC for 48 h. GFAP staining to visualize astrocyte morphology and network. Neuronal cell death was monitored by co-labeling with the dye propidium iodide (PI, red) and Purkinje neuron marker Calbindin (blue). Scale bars: 20 μm

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