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Fig. 8 | Acta Neuropathologica Communications

Fig. 8

From: Age-dependent dopamine transporter dysfunction and Serine129 phospho-α-synuclein overload in G2019S LRRK2 mice

Fig. 8

Age-dependent overload of Serine129-phosphorylated α-synuclein (pSer129 α-syn) in G2019S knock-in (KI) mice. Representative microphotographs and relative quantifications of α-syn and pSer129 α-syn immunostaining in the striatum of 12-month-old (a, b) and 3-month-old (c, d) G2019S KI mice and WT controls. Data are expressed as mean ± SEM of 8 (a, b) or 6 (c, d) mice per group. Statistical analysis was performed by the Student t-test, two tailed for unpaired data. *p < 0.05 different from WT

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