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Table 3 3Rtau/4Rtau mRNA ratios in single LC neurons

From: Locus coeruleus cellular and molecular pathology during the progression of Alzheimer’s disease

Clinical diagnosis 3R/4R ratio
0 insert
3R/4R ratio
1 insert
3R/4R ratio
2 inserts
NCI 1.36 ± 0.11 1.12 ± 0.14 1.25 ± 0.07
aMCI 1.02 ± 0.09* 0.81 ± 0.08* 0.92 ± 0.12*
AD 0.98 ± 0.1* 0.83 ± 0.05* 0.89 ± 0.13*
  1. * p < 0.05 via one-way ANOVA with Bonferroni correction