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Table 3 3Rtau/4Rtau mRNA ratios in single LC neurons

From: Locus coeruleus cellular and molecular pathology during the progression of Alzheimer’s disease

Clinical diagnosis

3R/4R ratio

0 insert

3R/4R ratio

1 insert

3R/4R ratio

2 inserts

NCI

1.36 ± 0.11

1.12 ± 0.14

1.25 ± 0.07

aMCI

1.02 ± 0.09*

0.81 ± 0.08*

0.92 ± 0.12*

AD

0.98 ± 0.1*

0.83 ± 0.05*

0.89 ± 0.13*

  1. * p < 0.05 via one-way ANOVA with Bonferroni correction