Table 1 Amyloigenic regions in Aβ24 and Aβ42 peptides predicted by the 11 indicated methods, and AMYLPRED2-derived consensus score
Method | Aβ24 | Aβ42 |
|---|---|---|
AGGRESCAN | 17–22 | 17–22, 30–42 |
AmyloidMutants | 4–12, 15–23 | 14–22, 34–42 |
Amyloidogenic Pattern | 16–21 | 16–21 |
Average Packing Density | 16–21 | 16–21, 32–37 |
Beta-strand contiguity | 15–20 | 15–20, 29–41 |
Hexapeptide Conf. Energy | 16–22 | 16–22, 29–42 |
NetCSSP | 1–23 | 1–23, 28–37 |
Pafig | 7–24 | 7–42 |
SecStr | 15–20 | 15–20 |
TANGO | 17–21 | 17–21, 29–41 |
WALTZ | 15–24 | 15–23, 28–42 |
AMYLPRED2 (CONSENSUS5) | 15–22 | 15–22, 29–42 |