Fig. 8
From: Neuropathology of supercentenarians - four autopsy case studies
ARTAG of Case 2. ARTAG (thorn-shaped astrocytes) is present in subpial areas of the basal forebrain (a). Granular or fuzzy astrocytes (GFA) are seen in the frontal (b) and occipital (c) cortex. In rare instances, possible GFAs are seen in the temporal white matter (d). Immunohistochemistry using monoclonal antibody specific to p-tau (AT8). Bar = 50 μm