Fig. 5
From: Spatio-temporal activation of caspase-8 in myeloid cells upon ischemic stroke
Absence of cleaved PARP, marker for apoptosis, in CD68-positive myeloid cells in stroke subject. Tissue from recent stroke case and healthy control subjected to double immunofluorescence staining using antibodies raised against CD68 and cleaved PARP, revealed an absence for the apoptosis marker in CD68-expressing myeloid cells. Tissue from colon was used as positive control for the cleaved PARP staining. Overview of the peri-infarct area of stroke case is depicted on top panel, whereas higher magnification images for both stroke case and controls are presented in the lower panels. Scale bars in images represent 10 μm