Skip to main content

Table 2 Summary of mouse tissue used for immunohistochemical analysis of novel antibodies

From: Novel antibodies to phosphorylated α-synuclein serine 129 and NFL serine 473 demonstrate the close molecular homology of these epitopes

Mouse line Treatment Fixative References
M83+/− Intramuscular injection of αS fibrils (motor impaired/terminal) 150 mM NaCl/ 70 % ethanol [28]
M83+/− Intramuscular injection of αS fibrils (motor impaired/terminal) Formalin [28]
M83+/− Cerebral injection of αS fibrils (3 months post-injection) 150 mM NaCl/ 70 % ethanol [26]
M83+/+ Naïve (7 month old; no phenotype) 150 mM NaCl/ 70 % ethanol  
M83+/+ Naïve (10–12 month old; motor impaired/terminal) 150 mM NaCl/ 70 % ethanol  
M20+/− Cerebral injection of αS fibrils (4 months post-injection) 150 mM NaCl/ 70 % ethanol [27]
M20+/− Cerebral injection of αS fibrils (4 months post-injection) Formalin [27]
WT Naïve 150 mM NaCl/ 70 % ethanol