Skip to main content

Table 4 GO term analysis of differentially expressing genes between 3.0Pa-loaded and 0.05Pa + turbulent flow-loaded group

From: Sustained expression of MCP-1 by low wall shear stress loading concomitant with turbulent flow on endothelial cells of intracranial aneurysm

Over-presented term in 0.05Pa + turbulent flow-loaded group
Accession Term P-value FDR
GO:0000786 nucleosome 7.7E-54 3.0E-51
GO:0006334 nucleosome assembly 6.4E-53 1.3E-50
GO:0000278 mitotic cell cycle 3.8E-26 5.1E-24
GO:0007067 mitosis 9.7E-26 9.6E-24
GO:0046982 protein heterodimerization activity 9.7E-24 7.7E-22
GO:0005654 nucleoplasm 5.6E-19 3.7E-17
GO:0060968 regulation of gene silencing 8.7E-15 4.7E-13
GO:0003677 DNA binding 9.5E-15 4.7E-13
GO:0005819 spindle 8.5E-14 3.7E-12
GO:0000775 chromosome, centromeric region 3.5E-13 1.4E-11
GO:0005634 nucleus 4.8E-13 1.7E-11
GO:0000777 condensed chromosome kinetochore 9.2E-13 3.1E-11
GO:0034080 CENP-A containing nucleosome assembly at centromere 5.9E-12 1.8E-10
GO:0007059 chromosome segregation 1.6E-11 4.5E-10
GO:0006260 DNA replication 1.1E-10 2.9E-09
GO:0030496 midbody 1.6E-10 3.9E-09
GO:0031536 positive regulation of exit from mitosis 2.1E-10 4.8E-09
GO:0000922 spindle pole 3.6E-10 7.8E-09
GO:0005876 spindle microtubule 1.9E-09 4.0E-08
GO:0006281 DNA repair 2.5E-09 5.0E-08
Under-presented term in 0.05Pa + turbulent flow-loaded group
Accession Term P-value FDR
GO:0002113 interleukin-33 binding 2.9E-07 5.9E-05
GO:0002114 interleukin-33 receptor activity 2.9E-07 5.9E-05
GO:0043032 positive regulation of macrophage activation 7.9E-07 1.1E-04
GO:0090197 positive regulation of chemokine secretion 1.0E-06 1.1E-04
GO:0004908 interleukin-1 receptor activity 1.5E-06 1.2E-04
GO:0002826 negative regulation of T-helper 1 type immune response 1.7E-06 1.2E-04
GO:0032754 positive regulation of interleukin-5 production 3.6E-05 2.1E-03
GO:0070698 type I activin receptor binding 5.9E-05 3.0E-03
GO:0071310 cellular response to organic substance 1.1E-04 4.9E-03
GO:0030617 inhibitory cytoplasmic mediator activity 1.2E-04 4.9E-03
  1. FDR false discovery rate