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Table 4 GO term analysis of differentially expressing genes between 3.0Pa-loaded and 0.05Pa + turbulent flow-loaded group

From: Sustained expression of MCP-1 by low wall shear stress loading concomitant with turbulent flow on endothelial cells of intracranial aneurysm

Over-presented term in 0.05Pa + turbulent flow-loaded group

Accession

Term

P-value

FDR

GO:0000786

nucleosome

7.7E-54

3.0E-51

GO:0006334

nucleosome assembly

6.4E-53

1.3E-50

GO:0000278

mitotic cell cycle

3.8E-26

5.1E-24

GO:0007067

mitosis

9.7E-26

9.6E-24

GO:0046982

protein heterodimerization activity

9.7E-24

7.7E-22

GO:0005654

nucleoplasm

5.6E-19

3.7E-17

GO:0060968

regulation of gene silencing

8.7E-15

4.7E-13

GO:0003677

DNA binding

9.5E-15

4.7E-13

GO:0005819

spindle

8.5E-14

3.7E-12

GO:0000775

chromosome, centromeric region

3.5E-13

1.4E-11

GO:0005634

nucleus

4.8E-13

1.7E-11

GO:0000777

condensed chromosome kinetochore

9.2E-13

3.1E-11

GO:0034080

CENP-A containing nucleosome assembly at centromere

5.9E-12

1.8E-10

GO:0007059

chromosome segregation

1.6E-11

4.5E-10

GO:0006260

DNA replication

1.1E-10

2.9E-09

GO:0030496

midbody

1.6E-10

3.9E-09

GO:0031536

positive regulation of exit from mitosis

2.1E-10

4.8E-09

GO:0000922

spindle pole

3.6E-10

7.8E-09

GO:0005876

spindle microtubule

1.9E-09

4.0E-08

GO:0006281

DNA repair

2.5E-09

5.0E-08

Under-presented term in 0.05Pa + turbulent flow-loaded group

Accession

Term

P-value

FDR

GO:0002113

interleukin-33 binding

2.9E-07

5.9E-05

GO:0002114

interleukin-33 receptor activity

2.9E-07

5.9E-05

GO:0043032

positive regulation of macrophage activation

7.9E-07

1.1E-04

GO:0090197

positive regulation of chemokine secretion

1.0E-06

1.1E-04

GO:0004908

interleukin-1 receptor activity

1.5E-06

1.2E-04

GO:0002826

negative regulation of T-helper 1 type immune response

1.7E-06

1.2E-04

GO:0032754

positive regulation of interleukin-5 production

3.6E-05

2.1E-03

GO:0070698

type I activin receptor binding

5.9E-05

3.0E-03

GO:0071310

cellular response to organic substance

1.1E-04

4.9E-03

GO:0030617

inhibitory cytoplasmic mediator activity

1.2E-04

4.9E-03

  1. FDR false discovery rate