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Fig. 5 | Acta Neuropathologica Communications

Fig. 5

From: Critical residues involved in tau binding to fyn: implications for tau phosphorylation in Alzheimer’s disease

Fig. 5

Correlation analysis of disease-related changes in tau and fyn in Alzheimer’s disease brain. a Total tau, expressed relative to neuron-specific enolase (NSE), and (b-f) tau phospho-epitopes Tau-1; CP13; pS214; pS262; and PHF-1, expressed relative to total tau were compared to the amount of fyn relative to NSE in post-mortem control and Alzheimer’s disease (AD) human brain. Pearson’s or Spearman’s rank correlation analysis showed significant correlation of fyn with CP13, pS262, and PHF-1 in control brain, but not in AD brain (details in Table 3), as indicated by a line of best fit

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