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Fig. 3 | Acta Neuropathologica Communications

Fig. 3

From: Critical residues involved in tau binding to fyn: implications for tau phosphorylation in Alzheimer’s disease

Fig. 3

Total tau is increased in AD brain whilst the amount of fyn is unchanged. a Western blots of control and Alzheimer’s disease (AD) post-mortem human brain tissue probed with antibodies to total tau (upper panel) and neuron-specific enolase (NSE, lower panel). The amount of tau was quantified relative to NSE in each sample (right). b Western blots of control and AD brain tissue probed with antibody against fyn (upper panel). The amount of fyn was quantified relative to NSE in each sample (right). Molecular weight markers (kDa) are shown on the left. Values represent mean ± SEM, n = 11–15 per group. Mann-Whitney non-parametric test, **p < 0.01, NS = not significant

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