Fig. 7

a, b Immunogold electron microscopy illustrating the direct association of PDDF with the nucleolus and a Cajal body labeled with the anti-fibrillarin antibody (a), and the nucleolus and a coilin-positive Cajal body (b). c A 53BP1-positive PDDF appears associated with a cluster of interchromatin granules (IGC) and a heterochromatin mass (hc). Scale bar: a = 500 nm, b = 400 nm and c = 100 nm