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Fig. 4 | Acta Neuropathologica Communications

Fig. 4

From: C9orf72 is differentially expressed in the central nervous system and myeloid cells and consistently reduced in C9orf72, MAPT and GRN mutation carriers

Fig. 4

Comparison of distinct C9orf72 TSSs expression values in frontal cortex of controls and FTD cases. Boxplots showing TSSs expression values in frontal cortex (indicated in tpm on the Y-axes) of seven controls, 5 FTD-C9orf72-HRE carriers, 5 FTD-GRN and 5 FTD-MAPT mutation carriers. Stark reduction for the highly expressed TSSs in CNS (S2A and S1 + S3b) is observed in all cases as compared to controls while there is an increase of AS1 TSS in C9orf72-HRE cases and of AS3 TSS in all FTD cases as compared to controls

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Acta Neuropathologica Communications

ISSN: 2051-5960

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