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Table 4 Distribution of LBAS in primary sensory neurons

From: Distribution of α-synuclein in the spinal cord and dorsal root ganglia in an autopsy cohort of elderly persons

  

S2 (n = 261)

S1 (n = 46)

L5 (n = 261)

L2 (n = 225)

DRG

Dorsal

Dorsal

DRG

Dorsal

Dorsal

DRG

Dorsal

Dorsal

DRG

Dorsal

Dorsal

(+)

root (+)

horn (+)

(+)

root (+)

horn (+)

(+)

root (+)

horn (+)

(+)

root (+)

horn (+)

DRG

(+)

43/43

43/43

12/12

12/12

45/45

45/45

34/35

35/35

(100)

(100)

(100)

(100)

(100)

(100)

(97.1)

(100)

(−)

47/218

108/218

8/34

15/34

32/216

102/216

21/190

83/190

(21.6)

(49.5)

(23.5)

(44.1)

(14.8)

(47.2)

(11.1)

(43.7)

Dorsal root

(+)

43/90

90/90

12/20

20/20

45/77

77/77

34/55

55/55

(47.8)

(100)

(60)

(100)

(58.4)

(100)

(61.8)

(100)

(−)

0/171

61/171

0/26

7/26

0/184

70/184

1/170

63/170

(0)

(35.7)

(0)

(26.9)

(0)

(38)

(0.6)

(37.1)

Dorsal horn

(+)

43/151

90/151

12/27

20/27

45/147

77/147

35/118

55/118

(28.5)

(59.6)

(44.4)

(74)

(30.6)

(52.4)

(29.7)

(46.6)

(−)

0/110

0/110

0/19

0/19

0/114

0/114

0/107

0/107

(0)

(0)

(0)

(0)

(0)

(0)

(0)

(0)

  1. Percentage of cases is given in parentheses
  2. DRG Dorsal root ganglion, LBAS Lewy body-related α-synucleinopathy
  3. (+) subjects with LBAS
  4. (−) subjects without LBAS