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Fig. 1 | Acta Neuropathologica Communications

Fig. 1

From: Hippocampal administration of chondroitinase ABC increases plaque-adjacent synaptic marker and diminishes amyloid burden in aged APPswe/PS1dE9 mice

Fig. 1

Western blot of human brevican from superior frontal gyrus of subjects with NCI (no cognitive impairment), MCI (mild cognitive impairment) and AD (Alzheimer’s disease). a Brevican blot of one lane from each group with intact brevican indicated by the arrow and GAPDH inset for normalization. b Quantification of intact brevican band density as a proportion of GAPDH density. Data were subject to one way ANOVA followed by Bonferroni multiple comparison test. Level of AD brevican is significantly elevated (p < 0.05) compared to NCI; (NCI n = 14, MCI n = 10, AD n = 14)

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