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Fig. 2 | Acta Neuropathologica Communications

Fig. 2

From: DNA copy number analysis of Grade II–III and Grade IV gliomas reveals differences in molecular ontogeny including chromothripsis associated with IDH mutation status

Fig. 2

In all chromosome maps, chromosomes are along the x-axis. The y-axis gives the percent of samples with deletion (red) or gain (blue) at that locus. For individual samples,chromosome abnormality calls are shown. a. Comparison of IDH wild type gliomas and IDH mutated gliomas. For each type of glioma, the chromosome map is shown. The top graph indicates the difference in the percent of samples with gains (blue) and deletions (red) at each locus between the two groups. Up means more common in IDH wild type gliomas and down means more common in IDH mutated gliomas. b. Hierarchical clustering of IDH wild type gliomas is shown below a chromosome map of all IDH wildtype gliomas. Grade is indicated by the rectangles next to the hierarchy tree with blue indicating grade IV and orange indicating lower grade. c. Hierarchical clustering for 1p/19q non-co-deleted, IDH mutated gliomas is shown below a chromosome map of all1p/19q non-co-deleted, IDH mutated gliomas. Grade is indicated by the rectangles next to the hierarchy tree with blue indicating grade IV and orange indicating lower grade

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