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Figure 6 | Acta Neuropathologica Communications

Figure 6

From: A novel mutation P112H in the TARDBP gene associated with frontotemporal lobar degeneration without motor neuron disease and abundant neuritic amyloid plaques

Figure 6

Comparison of Aß patterns between different human brain samples. The relative abundance of different variants of Aß in detergent preparations from human temporal lobe samples was analyzed by urea-SDS-PAGE/immunoblot. For comparison, the indicated synthetic Aß peptides were loaded (S). P2, P1, AD1, AD2 temporal lobe samples from proband (P1), patient 2 (P2) and two Alzheimer’s disease (AD1 and AD2) patients. Aß immunoblots of the detergent fractions probed with mAb 6E10. 5 μg of total protein of each sample was loaded.

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Acta Neuropathologica Communications

ISSN: 2051-5960

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