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Table 1 Age, gender, clinical diagnosis, cause of death, post-mortem interval, and brain weight for control, prePD, and PD cases

From: Loss of angiotensin II receptor expression in dopamine neurons in Parkinson’s disease correlates with pathological progression and is accompanied by increases in Nox4- and 8-OH guanosine-related nucleic acid oxidation and caspase-3 activation

All prePD and PD cases are α-synuclein Braak stage 6
Case Group Age (y)/ gender Clinical diagnosis Cause of death PMI (h) Brain weight (g)
1 AMC 67/M Leukemia Pneumonia 5.5 1450
2 AMC 78/M Atherosclerosis Pulmonary Embolism 19.0 1070
3 AMC 87/F Atherosclerosis/diabetes Renal failure 13.0 NA
4 AMC 85/M Adenocarcinoma Metastasis 11.0 1210
5 AMC 76/M Atherosclerosis/diabetes Heart failure 3.0 1480
6 AMC 87/M Atherosclerosis Aneurysm rupture 5.0 1375
7 AMC 79/M Atherosclerosis Heart failure 22.5 1550
8 PrePD 79/M AD Pneumonia 14.5 1100
9 PrePD 86/M COPD pneumonia 20.5 1175
10 PrePD 69/M Primary aphasia Unknown <12.0 1475
11 PD 85/M PD/dementia Heart failure 5.5 NA
12 PD 76/M PD/dementia Pneumonia 7.0 1490
13 PD 84/M PD/dementia Unknown 1.5 1250
14 PD 66/F PD/dementia Unknown 10.0 1050
15 PD 77/F PD/AD Pneumonia 5.5 1075
  1. Abbreviations: COPD chronic obstructive pulmonary disease and PMI post-mortem interval.