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Table 1 Age, gender, clinical diagnosis, cause of death, post-mortem interval, and brain weight for control, prePD, and PD cases

From: Loss of angiotensin II receptor expression in dopamine neurons in Parkinson’s disease correlates with pathological progression and is accompanied by increases in Nox4- and 8-OH guanosine-related nucleic acid oxidation and caspase-3 activation

All prePD and PD cases are α-synuclein Braak stage 6

Case

Group

Age (y)/ gender

Clinical diagnosis

Cause of death

PMI (h)

Brain weight (g)

1

AMC

67/M

Leukemia

Pneumonia

5.5

1450

2

AMC

78/M

Atherosclerosis

Pulmonary Embolism

19.0

1070

3

AMC

87/F

Atherosclerosis/diabetes

Renal failure

13.0

NA

4

AMC

85/M

Adenocarcinoma

Metastasis

11.0

1210

5

AMC

76/M

Atherosclerosis/diabetes

Heart failure

3.0

1480

6

AMC

87/M

Atherosclerosis

Aneurysm rupture

5.0

1375

7

AMC

79/M

Atherosclerosis

Heart failure

22.5

1550

8

PrePD

79/M

AD

Pneumonia

14.5

1100

9

PrePD

86/M

COPD

pneumonia

20.5

1175

10

PrePD

69/M

Primary aphasia

Unknown

<12.0

1475

11

PD

85/M

PD/dementia

Heart failure

5.5

NA

12

PD

76/M

PD/dementia

Pneumonia

7.0

1490

13

PD

84/M

PD/dementia

Unknown

1.5

1250

14

PD

66/F

PD/dementia

Unknown

10.0

1050

15

PD

77/F

PD/AD

Pneumonia

5.5

1075

  1. Abbreviations: COPD chronic obstructive pulmonary disease and PMI post-mortem interval.