Skip to main content

Table 1 Demographic characteristics of cohorts

From: Phosphorylated α-synuclein in Parkinson’s disease: correlation depends on disease severity

  Baseline (N = 95) Final (N = 95) UW-collaborative (N = 209) LRRK2 (N = 30)
Age, y (mean ± SD) 61.08 ± 8.91 63.08 ± 8.68 65.94 ± 10.54 53.13 ± 13.88
Sex F/M (% Male) 35/60 (63%) 35/60 (63%) 52/157 (75%) 15/15 (50%)
Duration of disease, y     
Mean ± SD 1.9 ± 1.41 4.02 ± 1.55 7.9 ± 6.48 --
Range 0 – 6 1 – 9 0 – 42  
MMSE     
Mean ± SD 28.85 ± 1.57 28.81 ± 1.48 28.47 ± 3.07 --
Range 23 – 30 22 – 30 11 – 30  
H&Y     
Median 2.0 2.0 2.0 --
Range 1.0 – 2.5 1.0 – 4.0 0.0 – 5.0  
UPDRS Total     
Mean ± SD 24.87 ± 12.50 40.73 ± 16.63 -- --
Range 0 – 61 9 – 88   
UPDRS Motor     
Mean ± SD 16.90 ± 9.52 27.36 ± 12.13 23.72 ± 11.87 5.20 ± 4.73
Range 0 – 50 5 – 62 0 – 71 0 – 20
Ps129 (pg/ml)     
Mean ± SD 114.66 ± 17.14 117.89 ± 17.92 74.01 ± 26.67 63.79 ± 22.73
Range 57.11 – 151.63 68.66 – 170.78 0.00 – 203.17 35.2 – 145.1
Total α-syn (pg/ml)     
Mean ± SD 630.83 ± 703.08 639.48 ± 677.95 553.61 ± 409.22 744.78 ± 1169.94
Range 186.3 – 6343.5 173.6 – 4523.0 140.0 – 2990.0 170.98 – 5735.08
Ratio     
Mean ± SD 0.2530 ± 0.1232 0.2688 ± 0.1433 0.177 ± 0.098 0.172 ± 0.132
Range 0.01 – 0.77 0.02 – 0.86 0.00 – 0.53 0.01 – 0.56
  1. Hoehn and Yahr.
  2. Unified Parkinson’s Disease Rating Scale3.