TTR is internalized by human SC. A) Double immunofluorescence of TTR (green) and EEA1 (red) showing colocalization spots between the 2 proteins in SC of FAP patients and normal control individuals (arrows). Scale bar 4 μm. B) Confocal representative image showing scarce colocalization between TTR (green) and lysosomes (red). Scale bar 3 μm.