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Table 1 Demographics and non-ALS pathology in 33 patients

From: TDP-43 pathology in the basal forebrain and hypothalamus of patients with amyotrophic lateral sclerosis

Average age at death (years) 62.7 (s = 9.09)
Male/Female n = 25/n = 8
Median duration (years) 3.1 (interquartile range, 2.2-4.8)
Brain weight (grams) 1348.6 (s = 156.97)
Any neurofibrillary pathology n = 24
Any parenchymal amyloid n = 9
Thal stage ≥ II n = 7
Braak stage ≥ III1 n = 4
CERAD ≥ “moderate” n = 2
CAA present2 n = 6
VBI present3 n = 3
LB pathology n = 0