Figure 1

Oligodendrocyte regulators are differentially expressed in various lesion types. MS lesions were dissected from frozen tissue and the expression level of the indicated mediators regulating oligodendrocytes were determined by qPCR. The absolute expression levels are given in terms of % GAPDH. Displayed is the mean of 6 normal white matter specimens, 6 demyelinated inactive, 4 demyelinated active, and 4 remyelinated lesion areas.