Skip to main content
Figure 1 | Acta Neuropathologica Communications

Figure 1

From: Mitochondrial abnormalities and low grade inflammation are present in the skeletal muscle of a minority of patients with amyotrophic lateral sclerosis; an observational myopathology study

Figure 1

Pathological changes in the muscles from ALS patients. A: Low power view of muscle with neurogenic changes showing small and large group atrophy (arrow). B: NADH-TR stain showing atrophic and hyperdense fibres and target fibres (arrow). C: Fibre necrosis (arrow). D: Inflammatory cell infiltration in the endomysium (arrow) and E: in the perimysium (arrow). F: Cytochrome oxidase negative fibres (arrow). G: Patchy over expression of HLA) - ABC in muscle fibres. H: Deposition of compliment (C5-9) in the endomysial capillaries.

Back to article page

Acta Neuropathologica Communications

ISSN: 2051-5960

Contact us