Skip to main content

Table 1 Allelic frequency of nucleotide change in NRAS and BRAF from deep amplicon sequencing of pathology specimens and buccal swabs

From: Oncogenic codon 13 NRAS mutation in a primary mesenchymal brain neoplasm and nevus of a child with neurocutaneous melanosis

Gene

NRAS

BRAF

Chromosome position (hg19)

1:115258745

7:140481411

Nucleotide change

c.37G > C

c.1397G > T

Amino acid change

p. Gly13Arg

p. Gly466Val

 

Allelic frequencies (%)

Mesenchymal brain tumor

58.0

0.0

Melanocytic nevus

33.0

32.0

Normal skin

4.8

0.0

Buccal swab

2.7

0.0

Mother buccal swab

0.0

0.0

Father buccal swab

0.0

0.0