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Table 3 Predicted enrichment costs and workload for single and pooled DNA samples

From: MotorPlex provides accurate variant detection across large muscle genes both in single myopathic patients and in pools of DNA samples

Technical step

Cost (€)

 

Single

PoolSeq

Haloplex Kit (96 samples)

16240,83

4263,22

Polymerase

86

22,575

AMPure XP beads

400

105

Validation and quantification of enriched target DNA

386,8

101,5

Total (total per sample)

17113.63 (213.92)

4492.29 (56.15)

Run Time

Total Time (h)

 

Single

PoolSeq

Enrichment procedure

4days

1day