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Table 1 Reported angiogenesis-related changes in serum, CSF and PBMCs of MS patients

From: Angiogenesis in multiple sclerosis and experimental autoimmune encephalomyelitis

Angiogenesis related molecules

Serum

CSF

PBMCs

VEGF-A

↑

[12],[59],[255]

↓

[53],[63]

↓

[59],[63]

VEGF-D

↑

[256]

    

VEGF-R3

↑

[256]

    

Angiopoietin-2

↑

[256]

    

Basic FGF

↑

[12]

↑

[257]

  

Endothelin-1

↑

[85],[184]

↑

[185]

↑

[258]

Nitric oxide and NOS

↑

[259]

↑

[111],[185]

↑

[260]

TNF-α

↑

[261]

↑

[258],[262],[263]

↑

[264]–[266]

TGF-β

↑

[267]

↑

[268]

↓

[269]

↓

[268]

IFN-γ

↑

[270]

↑

[75]

↑

[265],[269]

MMP-2

↑

[271]

↑

[272]

↑

[273]

MMP-9

↑

[271],[274]

↑

[275],[276]

↑

[273]

TIMP-1

↑

[274]

↓

[277]

↓

[278]

sCD146

  

↑

[279]

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