Figure 8

CMV; fetus 35 weeks. a: Fixed brain showing a well-defined area of cortical malformation in the peri-Sylvian region (arrows). b: The cerebral cortex shows increased cellularity in the molecular layer of the cortex (arrow) (H&E). c: Reticulin stain shows the increased collagen in the leptomeninges and around blood vessels dipping into the cortex. d: The cerebellar cortex is also involved and abnormally folded with extensive disruption of its superficial layers (H&E). e: A typical large nuclear inclusion of CMV (H&E).