Figure 3

Detection of EphA4, Aβ and pTau in consecutive brain slides of AD hippocampus. Immunohistochemical detection of A) EphA4 (DAB i.e. brown colour), B) Aβ and C) pTau in the dentate gyrus (DG) and stratum lacunosum (SL) of consecutive brain slides in AD (Braak 6 C, case #30 in Table 1) indicated with the vessel in the right lower corner. Arrows are pointing out the same plaques. A 2x higher magnification is shown for EphA4, Aβ and pTau in D), E) and F) respectively in consequent brain slides for a different patients with AD (Braak 6 C, case #31 in Table 1). All sections were counterstained with hematoxylin. Scale bar 100 μm for A-C and 50 μm for D-F.