Figure 5

Separation of peripapillary OCT circle scans from 7-month-old Ppt1 ^+/+ and Ppt1 ^-/- mice into composite layers. A: Representative excerpts of OCT circle scans from Ppt1 ^+/+ and Ppt1 ^-/- mice with indication of the defined layers. Scale bar: 200 μm. B: Inner but not outer retina thickness was significantly reduced in Ppt1 ^-/- mice (n = 4 per group). Student’s t-test. **P < 0.01. C: Significant thinning was detected in NFL/GCL/IPL and INL of Ppt1 ^-/- mice, but not in other retinal layers. Student’s t-test. * P < 0.05, **P < 0.01. n.s. = not significant.