Table 1 List of experiments performed on M83 mice
Experiment | Passage Inoculum (brain equivalent or quantity of recα-syn) | Survival period (d.p.i.) | Median/maximal survival (days old) | αSddetection by Western blot or ELISA or IHC |
|---|---|---|---|---|
1 | P1 (2 mg) | 129 +/− 19 | 192/217 | 8/8 |
2 | αSrec fib (10 μg) | 106 +/− 27 | 145/216 | 6/6 |
3 | P2 (10 mg) | 105 +/− 23 | 146/181 | 5/5 |
4 | P2 (2 mg) | 107 +/− 12 | 147/173 | 8/8 |
5 | P2 (0.4 mg) | 140 +/− 33 | 188/232 | 9/10 |
6 | P2 Stx hippocampus (2 mg) | 130 +/− 13 | 171/196 | 5/5 |
7 | P2 Stx cerebellum (2 mg) | 131 +/− 50 | 159/187 | 4/4 |
8 | P2 spinal cord (2 mg) | 113 +/− 22 | 163/174 | 5/5 |
9 | P2 cerebral cortex (2 mg) | 224 +/− 93 | 219/472 | 5/5 |
10 | P2 spleen (2 mg) | 378 +/− 98 | 374/584 | 4/5 |