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Table 2 Tissue samples, demographics of autistic and control subjects, brain weight, and changes during processing

From: Brain-region–specific alterations of the trajectories of neuronal volume growth throughout the lifespan in autism

Group

Case number

Sex

Age (years)

PMI (h)

Brain weight (g)

H

Fixation (days)

Dehydration (days)

Weight loss (%)

A

1

M

4

30

1,280

R

4,560

28

49

A

2

F

5

13.2

1,390

R

1,568

28

52

A

3

M

7

25

1,610

R

330

37

55

A

4

M

8

22.2

1,570

R

196

36

45

A

5

F

11

12.9

1,460

L

308

34

52

A

6

M

13

8

1,470

L

75

33

39

A

7

F

17

25

1,580

L

470

36

51

A

8

F

21

50

1,108

R

136

35

43

A

9

M

22

25

1,375

R

1,034

39

38

A

10

M

23

14

1,610

R

533

45

60

A

11

M

36

24

1,480

R

721

37

44

A

12

M

52

27.6

1,625

R

1,650

39

40

A

13

M

56

3.3

1,570

R

692

38

52

A

14

M

60

26.5

1,210

R

398

39

38

Average

21.9

1,453

 

905

36

47

SD

11.4

162

 

1,160

4

7

p< (difference between autistic and control groups)

ns

ns

 

ns

ns

ns

C

1

F

4

17

1,530

R

126

41

49

C

2

F

4

21

1,222

R

233

30

43

C

3

M

7

12

1,240

R

130

41

51

C

4

F

8

20

1,222

R

650

36

51

C

5

M

14

20

1,464

R

1,067

38

44

C

6

F

15

9

1,250

R

372

41

49

C

7

F

20

9

1,340

R

245

37

52

C

8

M

23

6

1,520

R

95

45

41

C

9

M

29

13

1,514

R

89

41

49

C

10

M

32

24

1,364

R

460

37

42

C

11

M

48

24

1,412

L

215

38

39

C

12

M

51

18

1,450

L

1,819

20

26

C

13

M

52

13

1,430

L

158

47

48

C

14

M

64

28

1,250

R

52

37

51

Average

16.7

1,372

 

408

38

45

SD

6.6

118

 

491

7

7

  1. PMI postmortem interval; h hours; H hemisphere; R right; L left; SD standard deviation.
  2. Fixation: duration (in days) of fixation in 10% buffered formalin.
  3. Dehydration: duration (in days) of dehydration in ethyl alcohol.
  4. Weight loss: decrease of hemispheric brain sample weight during dehydration in ethyl alcohol.