Figure 4

Neuronal soma volume distribution in autistic (red line) and control (green line) subjects in brain structures with the largest neurons (Purkinje cells and neurons in the magnocellular basal complex), moderate size neurons (thalamus and amygdala), and small neurons (caudate nucleus and nucleus accumbens). Graphs show a significant shift towards small size in 4- to 8-year-old autistic subjects in all three neuronal size categories and a rather uniform reduction of differences in volume distribution in 11- to 60-year-old autistic subjects.