Figure 2From: The prognostic role of intragenic copy number breakpoints and identification of novel fusion genes in paediatric high grade glioma Clinicopathological correlates of intragenic copy number breaks in paediatric high grade glioma . (a) Number of intragenic breaks per sample in a series of 100 pHGG. (b) Kaplan-Meier plot of overall survival stratified by number of intragenic breaks per sample. Pink: no breaks; Red: more than 10 breaks per sample; Grey: rest. (c-f) Boxplot of number of intragenic breaks per sample separated by - (c) WHO grade. Orange: grade III; Brown: grade IV. (d) Previous radiation treatment for an earlier malignancy. Grey: primary pHGG; Purple: post-irradiation; (e) Age at diagnosis. Yellow: infant (<3Â years old); Dark yellow: older children (>3Â years old). (f) H3F3A status. Blue: G34R/V; Green: K27M; Grey: wild-type.Back to article page