Figure 7

Size increase with granular-dot like inclusions in OAH neurons and atrophic DL neurons but not in ON. In DL and OAH, size of neuron without inclusion was smaller than that of granular/dot-like deposits (perimeter: DL; p = 0.003, OAH; p < 0.001)(area: DL; p = 0.008, OAH; p < 0.001) (a, b, d, e). In OAH and ON, neuronal size remained unchanged between control and without inclusion (b, c, e, f). A decrease in CI of neurons without inclusion was consistent in all groups (DL; p < 0.001, OAH; p < 0.001, ON; p = 0.001) (g-i). p: p value.