|
Codon 129
|
Gender
|
Age (years)
|
Disease duration (Months)
|
Frequency of granular PrP deposits in the frontal subcortical white matter (intensity score)
|
|---|
|
MM
|
M
|
75
|
2.5
|
0
|
|
MM
|
M
|
76
|
3
|
2
|
|
MM
|
F
|
66
|
6
|
3
|
|
MM
|
M
|
89
|
13
|
1
|
|
MM
|
F
|
81
|
3
|
1
|
|
MM
|
M
|
62
|
3
|
2
|
|
MM
|
F
|
74
|
5
|
2
|
|
MM
|
F
|
63
|
3
|
3
|
|
MM
|
F
|
74
|
3
|
1
|
|
Average MM
|
M:F = 4:5
|
73.3
|
4.6
|
1.67
|
|
MV
|
F
|
73
|
7
|
1
|
|
MV
|
F
|
67
|
2
|
1
|
|
MV
|
F
|
70
|
10
|
0
|
|
MV
|
M
|
75
|
2
|
1
|
|
MV
|
M
|
62
|
11
|
0
|
|
MV
|
M
|
63
|
17
|
0
|
|
MV
|
M
|
56
|
11
|
2
|
|
MV
|
M
|
62
|
3
|
2
|
|
MV
|
M
|
77
|
12
|
3
|
|
MV
|
M
|
68
|
3
|
1
|
|
Average MV
|
M:F = 7:3
|
67.3
|
7.8
|
1.1
|
|
VV
|
M
|
69
|
9
|
0
|
|
VV
|
F
|
57
|
3
|
1
|
|
VV
|
F
|
72
|
5
|
1
|
|
VV
|
F
|
81
|
9
|
2
|
|
VV
|
F
|
81
|
3
|
0
|
|
VV
|
M
|
83
|
3
|
2
|
|
VV
|
M
|
61
|
2
|
3
|
|
Average VV
|
M:F = 3:4
|
72
|
4.8
|
1.29
|
- Cases with Codon 129MM, MV and VV alleles were used. The table also lists the age at death, duration of illness and the density of granular PrP in the white matter. The case numbers are cross-referenced in Figure 4.
