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Table 5 Summary of intensity scores in sporadic CJD

From: Filamentous white matter prion protein deposition is a distinctive feature of multiple inherited prion diseases

 

Scores for granular PrP (number of cases)

 

sCJD, codon 129 genotype

Score 0

Score 1

Score2

Score 3

Significance

129MM

1

3

3

2

MM vs. MV: 0.23 (n.s.)

129MV

3

4

2

1

MV vs. VV: 0.72 (n.s.)

129VV

2

2

2

1

MM vs. VV: 0.48 (n.s.)

  1. The left columns indicated the genotype of the codon 129 polymorphism, the subsequent columns the number of cases with the indicated scores (0–3) and the right columns the statistical analysis of the scores between the different codon 129 genotypes. No statistically significant difference in the intensity scores are seen between cases with codon 129 MM, MV or VV.
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Acta Neuropathologica Communications

ISSN: 2051-5960

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