Representative images of NGFR and SMA immunohistochemistry showing the stromal NGFR+
cells in ketamine cystitis tissue and a serial section demonstrating that NGFR+
cells are SMA-
. SMA+ labelling of vascular walls also highlights the appearance of prominent blood vessels in the bladder wall of ketamine cystitis biopsies. NGFR+ peripheral nerve fascicles are arrowed in ketamine cystitis and “control” non-diseased bladder taken during radical prostatectomy. Scale bar represents 100 μm.