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Table 1 The list of antibodies used in immunohistochemistry and immunoprecipitation experiments

From: The Arctic AβPP mutation leads to Alzheimer’s disease pathology with highly variable topographic deposition of differentially truncated Aβ

Antibody Epitope/Target Manufacturer
N-terminal Aβ-antibodies
mAb 82E1 Neoepitope Aβ1-5 IBL, Hamburg, Germany
mAb 6E10 Aβ5-10 Covance, Berkeley, CA, USA
Mid-domain Aβ-antibodies
mAb 6F/3D Aβ8-17 Novocastra, Newcastle, U.K.
mAb 4G8 Aβ17-24 Covance
C-terminal Aβ-antibodies
rpAb 40 Aβx-40, neoepitope Biosource/Invitrogen, Camarillo CA, USA
rpAb 42 Aβx-42, neoepitope Biosource/Invitrogen
Special Aβ-antibodies
mAb 27 Aβ20-24 with Arc-mutation p.E22G Lord et al. 2009 [19]
mAb 2-48 Aβ3pE Synaptic Systems, Göttingen, Germany
rpAb 11pE Aβ11pE Synaptic Systems
Antibodies to cellular alterations
mAb AT8 Hyperphosphorylated tau Innogenetics, Zwijndrecht, Belgium
mAb GFAP Glial fibrillary acidic protein Dako, Glostrup, Denmark
mAb HLA-DP, DQ, DR Microglial cells Dako
rpAb Iba1 Microglial cells Wako, Osaka, Japan
rpAbα1-antitrypsin Lysosomes Dako
rpAb cathepsin D Lysosomes Dako (production discontinued)
  1. Abbreviations: mAb mouse monoclonal antibody, rpAb rabbit polyclonal antibody.