Skip to main content

Table 1 The list of antibodies used in immunohistochemistry and immunoprecipitation experiments

From: The Arctic AβPP mutation leads to Alzheimer’s disease pathology with highly variable topographic deposition of differentially truncated Aβ

Antibody

Epitope/Target

Manufacturer

N-terminal Aβ-antibodies

mAb 82E1

Neoepitope Aβ1-5

IBL, Hamburg, Germany

mAb 6E10

Aβ5-10

Covance, Berkeley, CA, USA

Mid-domain Aβ-antibodies

mAb 6F/3D

Aβ8-17

Novocastra, Newcastle, U.K.

mAb 4G8

Aβ17-24

Covance

C-terminal Aβ-antibodies

rpAb 40

Aβx-40, neoepitope

Biosource/Invitrogen, Camarillo CA, USA

rpAb 42

Aβx-42, neoepitope

Biosource/Invitrogen

Special Aβ-antibodies

mAb 27

Aβ20-24 with Arc-mutation p.E22G

Lord et al. 2009 [19]

mAb 2-48

Aβ3pE

Synaptic Systems, Göttingen, Germany

rpAb 11pE

Aβ11pE

Synaptic Systems

Antibodies to cellular alterations

mAb AT8

Hyperphosphorylated tau

Innogenetics, Zwijndrecht, Belgium

mAb GFAP

Glial fibrillary acidic protein

Dako, Glostrup, Denmark

mAb HLA-DP, DQ, DR

Microglial cells

Dako

rpAb Iba1

Microglial cells

Wako, Osaka, Japan

rpAbα1-antitrypsin

Lysosomes

Dako

rpAb cathepsin D

Lysosomes

Dako (production discontinued)

  1. Abbreviations: mAb mouse monoclonal antibody, rpAb rabbit polyclonal antibody.