Figure 9

Consecutive sections from Sw2 patient’s frontal cortex. GFAP positivity (a) is accentuated within the Aβ_x-40- positive plaques (b) and it appears to be due to denser network of processes, since astrocyte cell bodies (four marked with an arrow) are mainly located around or outside the plaques (asterisks). c: The Aβ deposition induces only slight and diffuse microglial (Iba1-positive) reaction, which does not seem to closely associate with the Aβ deposits in (b). (bar in a 200 μm for all panels).