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Table 4 Dysregulation of TDP-43 binding miRNAs in lymphoblastoid cell lines (LCLs) derived from sporadic and genetic ALS patients compared to LCLs of healthy controls

From: Systemic dysregulation of TDP-43 binding microRNAs in amyotrophic lateral sclerosis

miRNA Sporadic ALS ALS caused by mutation in
TDP-43 SOD1 FUS C9ORF72
miR-132-5p ↓* ↓* ↓** ↓*
miR-132-3p ↓* ↓* ↓** ↓*
miR-143-5p ↓** ↓* ↓* ↓* ↓*
miR-143-3p ↓* t t ↓** ↓*
miR-574-5p ↓* t ↓* ↓**
miR-574-3p ↓** t ↓** ↓*
miR-558-3p
miR-663a ↓*
let-7b ↓** ↓*
  1. ↔: no change; ↓: downregulation; *,**: level of significance; t: trend.