Skip to main content
Figure 8 | Acta Neuropathologica Communications

Figure 8

From: The influence of DNA repair on neurological degeneration, cachexia, skin cancer and internal neoplasms: autopsy report of four xeroderma pigmentosum patients (XP-A, XP-C and XP-D)

Figure 8

Case 4 XP-C Neuropathologic changes. A: The cerebellum shows focal loss of Purkinje cells (x100). B-E: Sections of optic nerves and geniculate nuclei reveal degenerative changes, including axonal loss, gliosis, and fibrosis (arrows) in keeping with the patient’s 10 year history of bilateral orbital exenterations (B. H&E x200; C. immunostain for Bielschowsky, x200 D. Masson stain, x200, E. LFB/PAS stain, x200). F. Dorsal root ganglia show severe neuronal loss and accompanying fibrosis (H&E, x200).

Back to article page