Figure 2From: The pathogenesis of cingulate atrophy in behavioral variant frontotemporal dementia and Alzheimer’s disease Photomicrographs of the posterior cingulate cortex (PC) in Alzheimer’s disease (AD, A) and the anterior cingulate cortex (AC) in FTLD-tau (B) and FTLD-TDP (C). Neuronal loss is obvious in these regions, with more severe degeneration observed in FTLD-tau (B), and a similar extent of degeneration observed in FTLD-TDP (C) and AD (A). Comparable levels of tau-immunopositivity in neurofibrillary tangles (A, inset) and Pick bodies (B, inset) was observed in PC in AD (A) and in AC in FTLD-tau (B). Sparse numbers of TDP-43 inclusions (C, inset) were found in cases with FTLD-TDP (C).Back to article page