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Figure 2 | Acta Neuropathologica Communications

Figure 2

From: The pathogenesis of cingulate atrophy in behavioral variant frontotemporal dementia and Alzheimer’s disease

Figure 2

Photomicrographs of the posterior cingulate cortex (PC) in Alzheimer’s disease (AD, A) and the anterior cingulate cortex (AC) in FTLD-tau (B) and FTLD-TDP (C). Neuronal loss is obvious in these regions, with more severe degeneration observed in FTLD-tau (B), and a similar extent of degeneration observed in FTLD-TDP (C) and AD (A). Comparable levels of tau-immunopositivity in neurofibrillary tangles (A, inset) and Pick bodies (B, inset) was observed in PC in AD (A) and in AC in FTLD-tau (B). Sparse numbers of TDP-43 inclusions (C, inset) were found in cases with FTLD-TDP (C).

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