Figure 5
From: Dysfunction of the mTOR pathway is a risk factor for Alzheimer’s disease
Molecular and cellular functions associated with mTOR-regulated genes differentially expressed in the frontal lobe of advanced AD patients. Molecular and cellular functions associated with genes differentially expressed in the frontal lobe of advanced AD patients (neocortical stage) compared to controls (176 genes). The chart shows the number of genes, expressed as a percentage of the total number, involved in each of the molecular and cellular functions deemed significant by IPA Ingenuity.