This work was supported by NIH/NIA Pre-Doctoral Fellowship 1F31AG043254 – 01, NIH/NIA grant R37 AG11762 (GDS), AG10124 and AG017586 as well as a grant from the Rainwater and Wyncote foundations, and from Cure PSP Society. Additional support came from NIH/NINDS (U24 NS072026), the NIH/NIA (P30 AG19610), the Arizona Department of Health Services (contract 211002, Arizona Alzheimer’s Research Center), the Arizona Biomedical Research Commission (contracts 4001, 0011, 05–901 and 1001 to the Arizona Parkinson’s Disease Consortium) and the Michael J. Fox Foundation for Parkinson’s Research.
Many thanks to Michele Hawk, M.S., D.V.M. for her technical contributions to this work. Special thanks to the staff of the CNDR Brain Bank: Theresa Schuck (manager), John Robinson, and Kevin Raible for their technical expertise and support and for supplying patient samples. Thanks also to the staff at the University of Michigan Alzheimer’s Disease Research Center for providing patient samples and information. Finally, many thanks to Sherry Beecher, Laura Cantwell, Beth Dombroski, Ph.D., Reteeka Sud, Ph.D., Evan Geller, and Lindsay Barbuto, as well as students Michael Wong and Luckmini Liyanage.
PSP Genetics Study Group information
Günter U. Höglinger49, Ulrich Müller50, Dennis W. Dickson8, Rosa Rademakers8, Rohan de Silva9, Irene Litvan10, Rachel G Gross29, John Hardy9, Peter Heutink42, Howard I Hurtig29, Matthew J Farrer43, Ryan J Uitti12, Jana Vandrovcova9, John C. van Swieten11, Zbignew K. Wszolek12, Eduardo Tolosa13, Pau Pastor14-16, Tamas Revesz17, Andrew J. Lees9,17, Elena Alonso14,15, Manuela Apfelbacher18, Steven E. Arnold44, Jesus Avila19, Thomas G. Beach20, Agnita J.W. Boon11, Wang Zheng Chiu11, Laura Donker Kaat11, Peter P. De Deyn45, Ranjan Duara46, Sebastiaan Engelborghs45, Yvette Bordelon21, Justo García de Yebenes22, NiCole A. Finch8, Owen A. Ross8, Robyn Flook23, Matthew P. Frosch24, Carles Gaig13, Douglas R. Galasko25, Eliezer Masliah25,26, Marla Gearing27, Bernadino Ghetti28, Salvatore Spina28, Neill R. Graff-Radford12, Murray Grossman29, Jorge L. Juncos30, Hans A. Kretzschmar31, Andrew P. Leiberman32, Kelly E Lyons47, Luke A. Massey9, Sean S. O’Sullivan9, Rajesh Pahwa47, Laura Silveira-Moriyama9, Catriona A. McLean33, Alberto Rabano34, Alex Rajput35, Sigrun Roeber31, Jonathan D. Rohrer36, Martin N. Rossor36, Wallace W Tourtellotte48, Claire Troakes37, Safa Al-Sarraj37, Juan C. Troncoso38, Vivianna M. Van Deerlin1,2, Jean Paul G. Vonsattel39, Charles L. White40 and Chris Zarrow41.
8Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA. 9Reta Lila Weston Institute, University College London (UCL) Institute of Neurology, London, UK. 10Department of Neurology, Division of Movement Disorders, University of Louisville, Louisville, Kentucky, USA. 11Department of Neurology, Erasmus University Medical Center, Rotterdam, The Netherlands. 12Department of Neurology, Mayo Clinic, Jacksonville, Florida, USA. 13Neurology Service, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Hospital Clínic, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, Barcelona, Spain. 14CIBERNED, Instituto de Salud Carlos III, Madrid, Spain. 15Neurogenetics laboratory, Division of Neurosciences, University of Navarra Center for Applied Medical Research, Pamplona, Spain. 16Department of Neurology, University of Navarra, Clínica Universidad de Navarra, Pamplona, Spain. 17Department of Molecular Neuroscience, Queen Square Brain Bank for Neurological Disorders, UCL Institute of Neurology, University College London, London, UK. 18Institute of Legal Medicine, University of Würzburg, Würzburg, Germany. 19Centro de Biologia Molecular Severo Ochoa (CSIC-UAM), Campus Cantoblanco, Universidad Autonoma de Madrid, Madrid, Spain. 20Civin Laboratory for Neuropathology, Banner Sun Health Research Institute, Sun City, Arizona, USA. 21Department of Neurology, University of California Los Angeles, Los Angeles, California, USA. 22Department of Neurology, Hospital Ramón y Cajal, Madrid, Spain. 23Centre for Neuroscience, Flinders University and Australian Brain Bank Network, Victoria, Australia. 24C.S. Kubik Laboratory for Neuropathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA. 25Department of Neurosciences, University of California San Diego, La Jolla, California, USA. 26Department of Pathology, University of California San Diego, La Jolla, California, USA. 27Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, USA. 28Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA. 29Department of Neurology, University of Pennsylvania Health System, Philadelphia, Pennsylvania, USA. 30Department of Neurology, Emory University, Atlanta, Georgia, USA. 31Institut für Neuropathologie, Ludwig-Maximilians-Universität and Brain Net Germany, Munich, Germany. 32Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan, USA. 33Victorian Brain Bank Network, Mental Health Research Institute, Victoria, Australia. 34Department of Neuropathology and Tissue Bank, Fundación Centro Investigación Enfermedades Neurológicas (CIEN), Instituto de Salud Carlos III, Madrid, Spain. 35Division of Neurology, Royal University Hospital, University of Saskatchewan, Saskatchewan, Canada. 36Department of Neurodegenerative Disease, Dementia Research Centre, UCL Institute of Neurology, UCL, London, UK. 37MRC London Neurodegenerative Diseases Brain Bank, Department of Clinical Neuroscience, Institute of Psychiatry, King’s College London, London, UK. 38Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. 39Department of Pathology and the Taub Institute for Research on Alzheimer’s Disease and the Aging Brain, Columbia University, New York, New York, USA. 40Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas, USA. 41Rancho Los Amigos National Rehabilitation Center, University of Southern California, Downey, California, USA. 42Department of Clinical Genetics, Vrije Universiteit (VU) Medical Center, Section Medical Genomics, Amsterdam, The Netherlands. 43Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada. 44Department of Psychiatry, Center for Neurobiology and Behavior, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA. 45Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium. 46Wien Center for Alzheimer’s Disease and Memory Disorders, Mt. Sinai Medical Center, Miami Beach, Florida, USA. 47Department of Neurology, University of Kansas Medical Center, Kansas City, Kansas, USA. 48Human Brain and Spinal Fluid Resource Center, Veterans Affairs West Los Angeles Healthcare Center, Los Angeles, California, USA. 49Department of Neurology, Philipps-Universität, Marburg, Germany. 50Institut for Humangenetik, Justus-Liebig-Universität, Giessen, Germany.