Skip to main content

Articles

Page 6 of 29

  1. Excessive amounts of amyloid β (Aβ) peptide have been suggested to dysregulate synaptic transmission in Alzheimer’s disease (AD). As a major type of glial cell in the mammalian brain, astrocytes regulate neuro...

    Authors: Cuong Pham, Karine Hérault, Martin Oheim, Steeve Maldera, Vincent Vialou, Bruno Cauli and Dongdong Li
    Citation: Acta Neuropathologica Communications 2021 9:44
  2. SORL1 is strongly associated with both sporadic and familial forms of Alzheimer’s disease (AD), but a lack of information about alternatively spliced transcripts currently limits our understanding of the role of

    Authors: Giulia Monti, Mads Kjolby, Anne Mette G. Jensen, Mariet Allen, Juliane Reiche, Peter L. Møller, Raquel Comaposada-Baró, Bartlomiej E. Zolkowski, Cármen Vieira, Margarita Melnikova Jørgensen, Ida E. Holm, Paul N. Valdmanis, Niels Wellner, Christian B. Vægter, Sarah J. Lincoln, Anders Nykjær…
    Citation: Acta Neuropathologica Communications 2021 9:43
  3. One of the main pathological hallmarks of Alzheimer’s disease (AD) is the intraneuronal accumulation of hyperphosphorylated tau. Passive immunotherapy is a promising strategy for the treatment of AD and there ...

    Authors: Rinie Bajracharya, David Brici, Liviu-Gabriel Bodea, Phillip W. Janowicz, Jürgen Götz and Rebecca M. Nisbet
    Citation: Acta Neuropathologica Communications 2021 9:42
  4. A fundamental property of infectious agents is their particulate nature: infectivity arises from independently-acting particles rather than as a result of collective action. Assemblies of the protein tau can e...

    Authors: Lauren V. C. Miller, Aamir S. Mukadam, Claire S. Durrant, Marina J. Vaysburd, Taxiarchis Katsinelos, Benjamin J. Tuck, Sophie Sanford, Olivia Sheppard, Claire Knox, Shi Cheng, Leo C. James, Michael P. Coleman and William A. McEwan
    Citation: Acta Neuropathologica Communications 2021 9:41
  5. The influence of the gut microbiota on traumatic brain injury (TBI) is presently unknown. This knowledge gap is of paramount clinical significance as TBI patients are highly susceptible to alterations in the g...

    Authors: Marta Celorrio, Miguel A. Abellanas, James Rhodes, Victoria Goodwin, Jennie Moritz, Sangeetha Vadivelu, Leran Wang, Rachel Rodgers, Sophia Xiao, Ilakkia Anabayan, Camryn Payne, Alexandra M. Perry, Megan T. Baldridge, Maria S. Aymerich, Ashley Steed and Stuart H. Friess
    Citation: Acta Neuropathologica Communications 2021 9:40
  6. The brain is the major target of congenital cytomegalovirus (CMV) infection. It is possible that neuron disorder in the developing brain is a critical factor in the development of neuropsychiatric diseases in ...

    Authors: Isao Kosugi, Yoshifumi Arai, Satoshi Baba, Hideya Kawasaki, Toshihide Iwashita and Yoshihiro Tsutsui
    Citation: Acta Neuropathologica Communications 2021 9:39
  7. Retina and optic nerve are sites of extra-cerebral manifestations of Alzheimer’s Disease (AD). Amyloid-β (Aβ) plaques and neurofibrillary tangles of hyperphosphorylated tau protein are detected in eyes from AD...

    Authors: Valentina Latina, Giacomo Giacovazzo, Federica Cordella, Bijorn Omar Balzamino, Alessandra Micera, Monica Varano, Cristina Marchetti, Francesca Malerba, Rita Florio, Bruno Bruni Ercole, Federico La Regina, Anna Atlante, Roberto Coccurello, Silvia Di Angelantonio, Pietro Calissano and Giuseppina Amadoro
    Citation: Acta Neuropathologica Communications 2021 9:38
  8. Peripheral biomarkers indicative of brain pathology are critically needed for early detection of Parkinson’s disease (PD). In this study, using NanoString and digital PCR technologies, we began by screening fo...

    Authors: Xiaodan Liu, Qilong Wang, Ying Yang, Tessandra Stewart, Min Shi, David Soltys, Genliang Liu, Eric Thorland, Eugene M. Cilento, Yiran Hou, Zongran Liu, Tao Feng and Jing Zhang
    Citation: Acta Neuropathologica Communications 2021 9:37
  9. Recurrent C11orf95-RELA fusions (RELAFUS) are the hallmark of supratentorial ependymomas. The presence of RELA as the fusion partner indicates a close association of aberrant NF-κB activity with tumorigenesis. Ho...

    Authors: Tatsuya Ozawa, Syuzo Kaneko, Frank Szulzewsky, Zhiwei Qiao, Mutsumi Takadera, Yoshitaka Narita, Tadashi Kondo, Eric C. Holland, Ryuji Hamamoto and Koichi Ichimura
    Citation: Acta Neuropathologica Communications 2021 9:36

    The Publisher Correction to this article has been published in Acta Neuropathologica Communications 2021 9:100

  10. MGMT-promoter methylation is associated with favorable outcome in glioblastoma. The aim of this study was to determine whether the absolute number of methylated Cytosine-Guanine-dinucleotide-(CpG-)sites within th...

    Authors: Sebastian Siller, Michael Lauseker, Philipp Karschnia, Maximilian Niyazi, Sabina Eigenbrod, Armin Giese and Joerg-Christian Tonn
    Citation: Acta Neuropathologica Communications 2021 9:35
  11. Cognitive dysfunction occurs in greater than 50% of individuals with multiple sclerosis (MS). Hippocampal demyelination is a prominent feature of postmortem MS brains and hippocampal atrophy correlates with co...

    Authors: Selva Baltan, Safdar S. Jawaid, Anthony M. Chomyk, Grahame J. Kidd, Jacqueline Chen, Harsha D. Battapady, Ricky Chan, Ranjan Dutta and Bruce D. Trapp
    Citation: Acta Neuropathologica Communications 2021 9:34
  12. Military veterans who experience blast-related traumatic brain injuries often suffer from chronic cognitive and neurobehavioral syndromes. Reports of abnormal tau processing following blast injury have raised ...

    Authors: Georgina Perez Garcia, Rita De Gasperi, Miguel A. Gama Sosa, Gissel M. Perez, Alena Otero-Pagan, Dylan Pryor, Rania Abutarboush, Usmah Kawoos, Patrick R. Hof, Dara L. Dickstein, David G. Cook, Sam Gandy, Stephen T. Ahlers and Gregory A. Elder
    Citation: Acta Neuropathologica Communications 2021 9:33
  13. Efforts to characterize the late effects of traumatic brain injury (TBI) have been in progress for some time. In recent years much of this activity has been directed towards reporting of chronic traumatic ence...

    Authors: Douglas H. Smith, Jean-Pierre Dollé, Kamar E. Ameen-Ali, Abigail Bretzin, Etty Cortes, John F. Crary, Kristen Dams-O’Connor, Ramon Diaz-Arrastia, Brian L. Edlow, Rebecca Folkerth, Lili-Naz Hazrati, Sidney R. Hinds, Diego Iacono, Victoria E. Johnson, C. Dirk Keene, Julia Kofler…
    Citation: Acta Neuropathologica Communications 2021 9:32
  14. Pain is a common non-motor symptom of Parkinson’s disease (PD), with current limited knowledge of its pathophysiology. Here, we show that peripheral inoculation of mouse alpha-synuclein (α-Syn) pre-formed fibr...

    Authors: Nelson Ferreira, Nádia Pereira Gonçalves, Asad Jan, Nanna Møller Jensen, Amelia van der Laan, Simin Mohseni, Christian Bjerggaard Vægter and Poul Henning Jensen
    Citation: Acta Neuropathologica Communications 2021 9:31
  15. Frontotemporal lobar degeneration proteinopathies with tau inclusions (FTLD-Tau) or TDP-43 inclusions (FTLD-TDP) are associated with clinically similar phenotypes. However, these disparate proteinopathies like...

    Authors: Lucia A. A. Giannini, Claire Peterson, Daniel Ohm, Sharon X. Xie, Corey T. McMillan, Katya Raskovsky, Lauren Massimo, EunRah Suh, Vivianna M. Van Deerlin, David A. Wolk, John Q. Trojanowski, Edward B. Lee, Murray Grossman and David J. Irwin
    Citation: Acta Neuropathologica Communications 2021 9:30
  16. Glioblastoma (GBM) is the most lethal primary brain tumor characterized by significant cellular heterogeneity, namely tumor cells, including GBM stem-like cells (GSCs) and differentiated GBM cells (DGCs), and ...

    Authors: Atsuhito Uneda, Kazuhiko Kurozumi, Atsushi Fujimura, Kentaro Fujii, Joji Ishida, Yosuke Shimazu, Yoshihiro Otani, Yusuke Tomita, Yasuhiko Hattori, Yuji Matsumoto, Nobushige Tsuboi, Keigo Makino, Shuichiro Hirano, Atsunori Kamiya and Isao Date
    Citation: Acta Neuropathologica Communications 2021 9:29
  17. Neurofibrillary tangles (NFTs) made of abnormally hyperphosphorylated tau are a hallmark of Alzheimer’s disease (AD) and related tauopathies. Regional distribution of NFTs is associated with the progression of...

    Authors: Longfei Li, Ruirui Shi, Jianlan Gu, Yunn Chyn Tung, Yan Zhou, Dingwei Zhou, Ruozhen Wu, Dandan Chu, Nana Jin, Kevin Deng, Jiawei Xu, Cheng-Xin Gong, Khalid Iqbal and Fei Liu
    Citation: Acta Neuropathologica Communications 2021 9:28
  18. Brain iron accumulation has been found to accelerate disease progression in amyloid-β(Aβ) positive Alzheimer patients, though the mechanism is still unknown. Microglia have been identified as key players in th...

    Authors: Boyd Kenkhuis, Antonios Somarakis, Lorraine de Haan, Oleh Dzyubachyk, Marieke E. IJsselsteijn, Noel F. C. C. de Miranda, Boudewijn P. F. Lelieveldt, Jouke Dijkstra, Willeke M. C. van Roon-Mom, Thomas Höllt and Louise van der Weerd
    Citation: Acta Neuropathologica Communications 2021 9:27
  19. Nucleolar stress has been implicated in the pathology and disease pathogenesis of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) from repeat expansions of GGGGCC in C9orf72 (C...

    Authors: Olubankole Aladesuyi Arogundade, Sandra Nguyen, Ringo Leung, Danielle Wainio, Maria Rodriguez and John Ravits
    Citation: Acta Neuropathologica Communications 2021 9:26
  20. Dementia with Lewy bodies (DLB) and Parkinson’s disease (PD) are clinically, pathologically and etiologically disorders embedded in the Lewy body disease (LBD) continuum, characterized by neuronal α-synuclein ...

    Authors: Stefanie Smolders, Stéphanie Philtjens, David Crosiers, Anne Sieben, Elisabeth Hens, Bavo Heeman, Sara Van Mossevelde, Philippe Pals, Bob Asselbergh, Roberto Dos Santos Dias, Yannick Vermeiren, Rik Vandenberghe, Sebastiaan Engelborghs, Peter Paul De Deyn, Jean-Jacques Martin, Patrick Cras…
    Citation: Acta Neuropathologica Communications 2021 9:25
  21. The cellular complexity of glioblastoma microenvironments is still poorly understood. In-depth, cell-resolution tissue analyses of human material are rare but highly necessary to understand the biology of this...

    Authors: George P. Cribaro, Elena Saavedra-López, Leire Romarate, Izaskun Mitxitorena, Laura R. Díaz, Paola V. Casanova, Meritxell Roig-Martínez, José M. Gallego, Ana Perez-Vallés and Carlos Barcia
    Citation: Acta Neuropathologica Communications 2021 9:24
  22. Mutations in the DNAJB6 gene have been identified as rare causes of myofibrillar myopathies. However, the underlying pathophysiologica mechanisms remain elusive. DNAJB6 has two known isoforms, including the nucle...

    Authors: Fang-Yuan Qian, Yu-Dong Guo, Juan Zu, Jin-Hua Zhang, Yi-Ming Zheng, Idriss Ali Abdoulaye, Zhao-Hui Pan, Chun-Ming Xie, Han-Chao Gao and Zhi-Jun Zhang
    Citation: Acta Neuropathologica Communications 2021 9:23
  23. Under normal conditions, astrocytes perform a number of important physiological functions centered around neuronal support and synapse maintenance. In neurodegenerative diseases including Alzheimer’s, Parkinso...

    Authors: Rajesh Kushwaha, Anshuman Sinha, Natallia Makarava, Kara Molesworth and Ilia V. Baskakov
    Citation: Acta Neuropathologica Communications 2021 9:22
  24. Amyotrophic lateral sclerosis (ALS) is a progressive fatal neurodegenerative disease that affects motoneurons. Mutations in superoxide dismutase 1 (SOD1) have been described as a causative genetic factor for A...

    Authors: Pablo Rozas, Cristina Pinto, Francisca Martínez Traub, Rodrigo Díaz, Viviana Pérez, Daniela Becerra, Patricia Ojeda, Jorge Ojeda, Madison T. Wright, Jessica Mella, Lars Plate, Juan Pablo Henríquez, Claudio Hetz and Danilo B. Medinas
    Citation: Acta Neuropathologica Communications 2021 9:21
  25. Primitive neuroectodermal tumors of the central nervous system (CNS-PNETs) are highly malignant neoplasms posing diagnostic challenge due to a lack of defining molecular markers. CNS neuroblastoma with forkhea...

    Authors: Andrey Korshunov, Konstantin Okonechnikov, Felix Schmitt-Hoffner, Marina Ryzhova, Felix Sahm, Damian Stichel, Daniel Schrimpf, David E. Reuss, Philipp Sievers, Abigail Kora Suwala, Ella Kumirova, Olga Zheludkova, Andrey Golanov, David T. W. Jones, Stefan M. Pfister, Marcel Kool…
    Citation: Acta Neuropathologica Communications 2021 9:20
  26. Synaptic pathology is a central event in Alzheimer’s disease (AD) and other neurodegenerative conditions, and investigation of synaptic proteins can provide valuable tools to follow synaptic dysfunction and lo...

    Authors: Elena Camporesi, Tammaryn Lashley, Johan Gobom, Juan Lantero-Rodriguez, Oskar Hansson, Henrik Zetterberg, Kaj Blennow and Bruno Becker
    Citation: Acta Neuropathologica Communications 2021 9:19
  27. Accumulation of misfolded host proteins is central to neuropathogenesis of numerous human brain diseases including prion and prion-like diseases. Neurons of retina are also affected by these diseases. Previous...

    Authors: James F. Striebel, Brent Race, Jacqueline M. Leung, Cindi Schwartz and Bruce Chesebro
    Citation: Acta Neuropathologica Communications 2021 9:17
  28. Multimerization is a key process in prion-like disorders such as Alzheimer’s disease (AD), since it is a requirement for self-templating tau and beta-amyloid amyloidogenesis. AT8-immunohistochemistry for hyper...

    Authors: Nora Bengoa-Vergniory, Elisavet Velentza-Almpani, Ana Maria Silva, Connor Scott, Mariana Vargas-Caballero, Magdalena Sastre, Richard Wade-Martins and Javier Alegre-Abarrategui
    Citation: Acta Neuropathologica Communications 2021 9:18
  29. Cancer cells optimize nutrient utilization to supply energetic and biosynthetic pathways. This metabolic process also includes redox maintenance and epigenetic regulation through nucleic acid and protein methy...

    Authors: Kazuhiro Tanaka, Takashi Sasayama, Hiroaki Nagashima, Yasuhiro Irino, Masatomo Takahashi, Yoshihiro Izumi, Takiko Uno, Naoko Satoh, Akane Kitta, Katsusuke Kyotani, Yuichi Fujita, Mitsuru Hashiguchi, Tomoaki Nakai, Masaaki Kohta, Yoichi Uozumi, Masakazu Shinohara…
    Citation: Acta Neuropathologica Communications 2021 9:16
  30. Transactive response DNA-binding protein 43 kDa (TDP-43) has been identified as the major component of ubiquitinated inclusions found in patients with sporadic amyotrophic lateral sclerosis (ALS). Increasing e...

    Authors: Xuebing Ding, Zhi Xiang, Chi Qin, Yongkang Chen, Haiyan Tian, Lin Meng, Danhao Xia, Han Liu, Jia Song, Jun Fu, Mingming Ma and Xuejing Wang
    Citation: Acta Neuropathologica Communications 2021 9:15
  31. An adequate understanding of the relationships between radiographic and genomic features in diffuse intrinsic pontine glioma (DIPG) is essential, especially in the absence of universal biopsy, to further chara...

    Authors: Xiaoting Zhu, Margot A. Lazow, Austin Schafer, Allison Bartlett, Shiva Senthil Kumar, Deepak Kumar Mishra, Phillip Dexheimer, Mariko DeWire, Christine Fuller, James L. Leach, Maryam Fouladi and Rachid Drissi
    Citation: Acta Neuropathologica Communications 2021 9:14
  32. Alpha-synuclein (αsyn) is the key component of proteinaceous aggregates termed Lewy Bodies that pathologically define a group of disorders known as synucleinopathies, including Parkinson’s Disease (PD) and Dem...

    Authors: Rachel Underwood, Mary Gannon, Aneesh Pathak, Navya Kapa, Sidhanth Chandra, Alyssa Klop and Talene A. Yacoubian
    Citation: Acta Neuropathologica Communications 2021 9:13
  33. Vascular dysregulation and cholinergic basal forebrain degeneration are both early pathological events in the development of Alzheimer’s disease (AD). Acetylcholine contributes to localised arterial dilatation...

    Authors: Shereen Nizari, Jack A. Wells, Roxana O. Carare, Ignacio A. Romero and Cheryl A. Hawkes
    Citation: Acta Neuropathologica Communications 2021 9:12
  34. Neurofibromatosis Type I (NF1) is a neurocutaneous genetic syndrome characterized by a wide spectrum of clinical presentations, including benign peripheral nerve sheath tumor called neurofibroma. These tumors ...

    Authors: Jean-Philippe Brosseau, Adwait A. Sathe, Yong Wang, Toan Nguyen, Donald A. Glass II, Chao Xing and Lu Q. Le
    Citation: Acta Neuropathologica Communications 2021 9:11
  35. Alzheimer’s disease (AD) is characterized by the accumulation of amyloid-β (Aβ) as senile plaques and cerebral amyloid angiopathy, and hyperphosphorylated tau (hp-tau) as neurofibrillary tangles in the brain. ...

    Authors: Yuta Takaichi, James K. Chambers, Kei Takahashi, Yoshiyuki Soeda, Riki Koike, Etsuko Katsumata, Chiaki Kita, Fuko Matsuda, Makoto Haritani, Akihiko Takashima, Hiroyuki Nakayama and Kazuyuki Uchida
    Citation: Acta Neuropathologica Communications 2021 9:10
  36. Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) represent two ends of the same disease spectrum of adult-onset neurodegenerative diseases that affect the motor and cognitive functions, re...

    Authors: Wan Yun Ho, Ira Agrawal, Sheue-Houy Tyan, Emma Sanford, Wei-Tang Chang, Kenneth Lim, Jolynn Ong, Bernice Siu Yan Tan, Aung Aung Kywe Moe, Regina Yu, Peiyan Wong, Greg Tucker-Kellogg, Edward Koo, Kai-Hsiang Chuang and Shuo-Chien Ling
    Citation: Acta Neuropathologica Communications 2021 9:9
  37. Authors: Tareq A. Juratli, Insa Prilop, Felix C. Saalfeld, Sylvia Herold, Matthias Meinhardt, Carina Wenzel, Silke Zeugner, Daniela E. Aust, Fred G. Barker 2nd, Daniel P. Cahill, Priscilla K. Brastianos, Sandro Santagata, Gabriele Schackert and Thomas Pinzer
    Citation: Acta Neuropathologica Communications 2021 9:8
  38. During the last decade, multiple clinical trials for Duchenne muscular dystrophy (DMD) have focused on the induction of dystrophin expression using different strategies. Many of these trials have reported a cl...

    Authors: Dominic Scaglioni, Francesco Catapano, Matthew Ellis, Silvia Torelli, Darren Chambers, Lucy Feng, Matthew Beck, Caroline Sewry, Mauro Monforte, Shawn Harriman, Erica Koenig, Jyoti Malhotra, Linda Popplewell, Michela Guglieri, Volker Straub, Eugenio Mercuri…
    Citation: Acta Neuropathologica Communications 2021 9:7
  39. In this study, we report the results of a comprehensive phenotyping of the retina of the AppNL-G-F mouse. We demonstrate that soluble Aβ accumulation is present in the retina of these mice early in life and progr...

    Authors: Marjan Vandenabeele, Lien Veys, Sophie Lemmens, Xavier Hadoux, Géraldine Gelders, Luca Masin, Lutgarde Serneels, Jan Theunis, Takashi Saito, Takaomi C. Saido, Murali Jayapala, Patrick De Boever, Bart De Strooper, Ingeborg Stalmans, Peter van Wijngaarden, Lieve Moons…
    Citation: Acta Neuropathologica Communications 2021 9:6
  40. Type 2 diabetes mellitus (T2D), characterised by peripheral insulin resistance, is a risk factor for dementia. In addition to its contribution to small and large vessel disease, T2D may directly damage cells o...

    Authors: Joanna J. Bury, Annabelle Chambers, Paul R. Heath, Paul G. Ince, Pamela J. Shaw, Fiona E. Matthews, Carol Brayne, Julie E. Simpson and Stephen B. Wharton
    Citation: Acta Neuropathologica Communications 2021 9:5
  41. Patients with pneumococcal meningitis are at risk for death and neurological sequelae including cognitive impairment. Functional genetic polymorphisms of macrophage migration inhibitory factor (MIF) alleles ha...

    Authors: Anne T. Kloek, Mercedes Valls Seron, Ben Schmand, Michael W. T. Tanck, Arie van der Ende, Matthijs C. Brouwer and Diederik van de Beek
    Citation: Acta Neuropathologica Communications 2021 9:4
  42. Focal malformations of cortical development (MCD) are linked to somatic brain mutations occurring during neurodevelopment. Mild malformation of cortical development with oligodendroglial hyperplasia in epileps...

    Authors: Thomas Bonduelle, Till Hartlieb, Sara Baldassari, Nam Suk Sim, Se Hoon Kim, Hoon-Chul Kang, Katja Kobow, Roland Coras, Mathilde Chipaux, Georg Dorfmüller, Homa Adle-Biassette, Eleonora Aronica, Jeong Ho Lee, Ingmar Blumcke and Stéphanie Baulac
    Citation: Acta Neuropathologica Communications 2021 9:3
  43. Concussion or mild traumatic brain injury is the most common form of traumatic brain injury with potentially long-term consequences. Current objective diagnosis and treatment options are limited to clinical as...

    Authors: Xuan Vinh To and Fatima A. Nasrallah
    Citation: Acta Neuropathologica Communications 2021 9:2

    The Data Descriptor to this article has been published in Scientific Data 2021 8:207

  44. Microglia-mediated neuroinflammation has been implicated in the pathogenesis of Alzheimer’s disease (AD). Although microglia in aging and neurodegenerative disease model mice show a loss of homeostatic phenoty...

    Authors: Akira Sobue, Okiru Komine, Yuichiro Hara, Fumito Endo, Hiroyuki Mizoguchi, Seiji Watanabe, Shigeo Murayama, Takashi Saito, Takaomi C. Saido, Naruhiko Sahara, Makoto Higuchi, Tomoo Ogi and Koji Yamanaka
    Citation: Acta Neuropathologica Communications 2021 9:1
  45. Demyelinated lesions in human pons observed after osmotic shifts in serum have been referred to as central pontine myelinolysis (CPM). Astrocytic damage, which is prominent in neuroinflammatory diseases like n...

    Authors: Melanie Lohrberg, Anne Winkler, Jonas Franz, Franziska van der Meer, Torben Ruhwedel, Nikoloz Sirmpilatze, Rakshit Dadarwal, Ronja Handwerker, Daniel Esser, Kerstin Wiegand, Christian Hagel, Andreas Gocht, Fatima Barbara König, Susann Boretius, Wiebke Möbius, Christine Stadelmann…
    Citation: Acta Neuropathologica Communications 2020 8:224
  46. Spinal muscular atrophy (SMA) is a neuromuscular disease characterized by loss of lower motor neurons, which leads to proximal muscle weakness and atrophy. SMA is caused by reduced survival motor neuron (SMN) ...

    Authors: Maximilian Paul Thelen, Brunhilde Wirth and Min Jeong Kye
    Citation: Acta Neuropathologica Communications 2020 8:223
  47. The neuropathology of Alzheimer’s disease (AD) is characterized by hyperphosphorylated tau neurofibrillary tangles (NFTs) and amyloid-beta (Aβ) plaques. Aβ plaques are hypothesized to follow a development sequ...

    Authors: Dominik Röhr, Baayla D. C. Boon, Martin Schuler, Kristin Kremer, Jeroen J. M. Hoozemans, Femke H. Bouwman, Samir F. El-Mashtoly, Andreas Nabers, Frederik Großerueschkamp, Annemieke J. M. Rozemuller and Klaus Gerwert
    Citation: Acta Neuropathologica Communications 2020 8:222
  48. Cancer-associated fibroblasts (CAFs) are activated fibroblasts constituting the major stromal components in many types of cancer. CAFs contribute to hallmarks of cancer such as proliferation, invasion and immu...

    Authors: Ming Li, Guoping Li, Juri Kiyokawa, Zain Tirmizi, Leland G. Richardson, Jianfang Ning, Saumya Das, Robert L. Martuza, Anat Stemmer-Rachamimov, Samuel D. Rabkin and Hiroaki Wakimoto
    Citation: Acta Neuropathologica Communications 2020 8:221
  49. Lipid peroxidation is a key to a portfolio of neurodegenerative diseases and plays a central role in α-synuclein (α-syn) toxicity, mitochondrial dysfunction and neuronal death, all key processes in the pathoge...

    Authors: M. Flint Beal, Jayandra Chiluwal, Noel Y. Calingasan, Ginger L. Milne, Mikhail S. Shchepinov and Victor Tapias
    Citation: Acta Neuropathologica Communications 2020 8:220
  50. The term “Primary age-related tauopathy” (PART) was coined in 2014 to describe the common neuropathological observation of neurofibrillary tangles without associated beta-amyloid (Aβ) pathology. It is possible...

    Authors: Andrew C. Robinson, Yvonne S. Davidson, Federico Roncaroli, James Minshull, Phillip Tinkler, Michael A. Horan, Antony Payton, Neil Pendleton and David M. A. Mann
    Citation: Acta Neuropathologica Communications 2020 8:215

Annual Journal Metrics