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  1. Environmental toxins are suspected to play a role in the pathogenesis of amyotrophic lateral sclerosis (ALS). In an attempt to determine which pathways these toxins can use to enter motor neurons we compared t...

    Authors: Roger Pamphlett and Stephen Kum Jew

    Citation: Acta Neuropathologica Communications 2013 1:13

    Content type: Research

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  2. Infantile neuroaxonal dystrophy (INAD) is a rare autosomal-recessive neurodegenerative disorder. Patients with INAD usually show neurological symptoms with infant onset and die in childhood. Recently, it was r...

    Authors: Yuichi Riku, Takeshi Ikeuchi, Hiroyo Yoshino, Maya Mimuro, Kazuo Mano, Yoji Goto, Nobutaka Hattori, Gen Sobue and Mari Yoshida

    Citation: Acta Neuropathologica Communications 2013 1:12

    Content type: Case report

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  3. Multiple neurodegenerative diseases are characterized by the abnormal accumulation of FUS protein including various subtypes of frontotemporal lobar degeneration with FUS inclusions (FTLD-FUS). These subtypes ...

    Authors: Edward B Lee, Jenny Russ, Hyunjoo Jung, Lauren B Elman, Lama M Chahine, Daniel Kremens, Bruce L Miller, H Branch Coslett, John Q Trojanowski, Vivianna M Van Deerlin and Leo F McCluskey

    Citation: Acta Neuropathologica Communications 2013 1:9

    Content type: Research

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  4. Sporadic, inherited and acquired prion diseases show distinct histological patterns of abnormal prion protein (PrP) deposits. Many of the inherited prion diseases show striking histological patterns, which oft...

    Authors: Lilla Reiniger, Ilaria Mirabile, Ana Lukic, Jonathan DF Wadsworth, Jacqueline M Linehan, Michael Groves, Jessica Lowe, Ronald Druyeh, Peter Rudge, John Collinge, Simon Mead and Sebastian Brandner

    Citation: Acta Neuropathologica Communications 2013 1:8

    Content type: Research

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  5. Neuron Glial 2 (NG2) cells are glial cells known to serve as oligodendrocyte progenitors as well as modulators of the neuronal network. Altered NG2 cell morphology and up-regulation as well as increased sheddi...

    Authors: Henrietta M Nielsen, Danyal Ek, Una Avdic, Camilla Orbjörn, Oskar Hansson, Robert Veerhuis, Annemieke JM Rozemuller, Arne Brun, Lennart Minthon and Malin Wennström

    Citation: Acta Neuropathologica Communications 2013 1:7

    Content type: Research

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  6. Rat models of Parkinson’s disease are widely used to elucidate the mechanisms underlying disease etiology or to investigate therapeutic approaches. Models were developed using toxins such as MPTP or 6-OHDA to ...

    Authors: Hemi Dimant, Suneil K Kalia, Lorraine V Kalia, Liya N Zhu, Laura Kibuuka, Darius Ebrahimi-Fakhari, Nikolaus R McFarland, Zhanyun Fan, Bradley T Hyman and Pamela J McLean

    Citation: Acta Neuropathologica Communications 2013 1:6

    Content type: Methodology article

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  7. Neuromyelitis optica (NMO) is a severe, disabling disease of the central nervous system (CNS) characterized by the formation of astrocyte-destructive, neutrophil-dominated inflammatory lesions in the spinal co...

    Authors: Maja Kitic, Sonja Hochmeister, Isabella Wimmer, Jan Bauer, Tatsuro Misu, Simone Mader, Markus Reindl, Kazuo Fujihara, Hans Lassmann and Monika Bradl

    Citation: Acta Neuropathologica Communications 2013 1:5

    Content type: Research

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  8. To investigate the association of DNA nucleotide excision repair (NER) defects with neurological degeneration, cachexia and cancer, we performed autopsies on 4 adult xeroderma pigmentosum (XP) patients with di...

    Authors: Jin-Ping Lai, Yen-Chun Liu, Meghna Alimchandani, Qingyan Liu, Phyu Phyu Aung, Kant Matsuda, Chyi-Chia R Lee, Maria Tsokos, Stephen Hewitt, Elisabeth J Rushing, Deborah Tamura, David L Levens, John J DiGiovanna, Howard A Fine, Nicholas Patronas, Sikandar G Khan…

    Citation: Acta Neuropathologica Communications 2013 1:4

    Content type: Research

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  9. The development of disease-modifying therapies for Alzheimer’s disease is hampered by our lack of understanding of the early pathogenic mechanisms and the lack of early biomarkers and risk factors.

    Authors: Sharon C Yates, Amen Zafar, Paul Hubbard, Sheila Nagy, Sarah Durant, Roy Bicknell, Gordon Wilcock, Sharon Christie, Margaret M Esiri, A David Smith and Zsuzsanna Nagy

    Citation: Acta Neuropathologica Communications 2013 1:3

    Content type: Research

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  10. Parkinson’s disease (PD) is a progressive neurodegenerative disorder typified by the presence of intraneuronal inclusions containing aggregated alpha synuclein (αsyn). The progression of parkinsonian pathology...

    Authors: Naomi P Visanji, Patricia L Brooks, Lili-Naz Hazrati and Anthony E Lang

    Citation: Acta Neuropathologica Communications 2013 1:2

    Content type: Review

    Published on:

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