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  1. Circumstantial evidence points to a pathological role of alpha-synuclein (aSyn; gene symbol SNCA), conferred by aSyn misfolding and aggregation, in Parkinson disease (PD) and related synucleinopathies. Several fi...

    Authors: Alberto Delaidelli, Mette Richner, Lixiang Jiang, Amelia van der Laan, Ida Bergholdt Jul Christiansen, Nelson Ferreira, Jens R. Nyengaard, Christian B. Vægter, Poul H. Jensen, Ian R. Mackenzie, Poul H. Sorensen and Asad Jan

    Citation: Acta Neuropathologica Communications 2021 9:105

    Content type: Research

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  2. The prevalence of congenital hydrocephalus has been estimated at 1.1 per 1000 infants when including cases diagnosed before 1 year of age after exclusion of neural tube defects. Classification criteria are bas...

    Authors: Florent Marguet, Myriam Vezain, Pascale Marcorelles, Séverine Audebert-Bellanger, Kévin Cassinari, Nathalie Drouot, Pascal Chambon, Bruno J. Gonzalez, Arie Horowitz, Annie Laquerriere and Pascale Saugier-Veber

    Citation: Acta Neuropathologica Communications 2021 9:104

    Content type: Case report

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  3. The blood–brain barrier is a dynamic endothelial cell barrier in the brain microvasculature that separates the blood from the brain parenchyma. Specialized brain endothelial cells, astrocytes, neurons, microgl...

    Authors: Parand Zarekiani, Marjolein Breur, Nicole I. Wolf, Helga E. de Vries, Marjo S. van der Knaap and Marianna Bugiani

    Citation: Acta Neuropathologica Communications 2021 9:103

    Content type: Research

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  4. Alzheimer’s disease (AD) is a progressive neurodegenerative disease with high prevalence rate among the elderly population. A large number of clinical studies have suggested repetitive transcranial magnetic st...

    Authors: Yangyang Lin, Jian Jin, Rongke Lv, Yuan Luo, Weiping Dai, Wenchang Li, Yamei Tang, Yuling Wang, Xiaojing Ye and Wei-Jye Lin

    Citation: Acta Neuropathologica Communications 2021 9:102

    Content type: Research

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  5. Glioblastoma (GBM) displays marked cellular and metabolic heterogeneity that varies among cellular microenvironments within a tumor. Metabolic targeting has long been advocated as a therapy against many tumors...

    Authors: Sajina Shakya, Anthony D. Gromovsky, James S. Hale, Arnon M. Knudsen, Briana Prager, Lisa C. Wallace, Luiz O. F. Penalva, H. Alex Brown, Bjarne W. Kristensen, Jeremy N. Rich, Justin D. Lathia, J. Mark Brown and Christopher G. Hubert

    Citation: Acta Neuropathologica Communications 2021 9:101

    Content type: Research

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  6. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Tatsuya Ozawa, Syuzo Kaneko, Frank Szulzewsky, Zhiwei Qiao, Mutsumi Takadera, Yoshitaka Narita, Tadashi Kondo, Eric C. Holland, Ryuji Hamamoto and Koichi Ichimura

    Citation: Acta Neuropathologica Communications 2021 9:100

    Content type: Publisher Correction

    Published on:

    The original article was published in Acta Neuropathologica Communications 2021 9:36

  7. Tau protein forms self-replicating assemblies (seeds) that may underlie progression of pathology in Alzheimer’s disease (AD) and related tauopathies. Seeding in recombinant protein preparations and brain homog...

    Authors: Brian D. Hitt, Jaime Vaquer-Alicea, Victor A. Manon, Joshua D. Beaver, Omar M. Kashmer, Jan N. Garcia and Marc I. Diamond

    Citation: Acta Neuropathologica Communications 2021 9:99

    Content type: Research

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  8. Short tandem repeat (STR) expansion disorders are an important cause of human neurological disease. They have an established role in more than 40 different phenotypes including the myotonic dystrophies, Fragil...

    Authors: Sanjog R. Chintalaphani, Sandy S. Pineda, Ira W. Deveson and Kishore R. Kumar

    Citation: Acta Neuropathologica Communications 2021 9:98

    Content type: Review

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  9. Zika virus (ZIKV), a mosquito-borne flavivirus, can cause severe eye disease and even blindness in newborns. However, ZIKV-induced retinal lesions have not been studied in a comprehensive way, mechanisms of ZI...

    Authors: Yi Li, Shuizhen Shi, Fan Xia, Chao Shan, Yonju Ha, Jing Zou, Awadalkareem Adam, Ming Zhang, Tian Wang, Hua Liu, Pei-Yong Shi and Wenbo Zhang

    Citation: Acta Neuropathologica Communications 2021 9:97

    Content type: Research

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  10. Oligodendrogliomas are defined by mutation in isocitrate dehydrogenase (NADP(+)) (IDH)1/2 genes and chromosome 1p/19q codeletion. World Health Organisation diagnosis endorses testing for 1p/19q codeletion to dist...

    Authors: Umma Habiba, Hirokazu Sugino, Roumyana Yordanova, Koki Ise, Zen-ichi Tanei, Yusuke Ishida, Satoshi Tanikawa, Shunsuke Terasaka, Ken-ichi Sato, Yuuta Kamoshima, Masahiko Katoh, Motoo Nagane, Junji Shibahara, Masumi Tsuda and Shinya Tanaka

    Citation: Acta Neuropathologica Communications 2021 9:95

    Content type: Research

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  11. Fluorescent staining of newly transcribed RNA via metabolic labelling with 5-ethynyluridine (EU) and click chemistry enables visualisation of changes in transcription, such as in conditions of cellular stress....

    Authors: Lisanne J. van’t Sant, Joshua J. White, Jan H. J. Hoeijmakers, Wilbert P. Vermeij and Dick Jaarsma

    Citation: Acta Neuropathologica Communications 2021 9:94

    Content type: Research

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  12. Cerebral amyloid angiopathy (CAA) contributes to accelerated cognitive decline in Alzheimer’s disease (AD) dementia and is a common finding at autopsy. The APOEε4 allele and male sex have previously been reported...

    Authors: Joseph S. Reddy, Mariet Allen, Charlotte C. G. Ho, Stephanie R. Oatman, Özkan İş, Zachary S. Quicksall, Xue Wang, Jiangli Jin, Tulsi A. Patel, Troy P. Carnwath, Thuy T. Nguyen, Kimberly G. Malphrus, Sarah J. Lincoln, Minerva M. Carrasquillo, Julia E. Crook, Takahisa Kanekiyo…

    Citation: Acta Neuropathologica Communications 2021 9:93

    Content type: Research

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  13. Misfolded forms of superoxide dismutase 1 (SOD1) with mutations associated with familial amyotrophic lateral sclerosis (fALS) exhibit prion characteristics, including the ability to act as seeds to accelerate ...

    Authors: Jacob I. Ayers, Guilian Xu, Kristy Dillon, Qing Lu, Zhijuan Chen, John Beckman, Alma K. Moreno-Romero, Diana L. Zamora, Ahmad Galaleldeen and David R. Borchelt

    Citation: Acta Neuropathologica Communications 2021 9:92

    Content type: Research

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  14. V-type immunoglobulin domain-containing suppressor of T-cell activation (VISTA) is a negative checkpoint regulator (NCR) that is involved in T-cell quiescence, inhibition of T-cell activation, and in myeloid c...

    Authors: Malte Borggrewe, Susanne M. Kooistra, Evelyn M. Wesseling, Fenja L. Gierschek, Maaike L. Brummer, Elizabeth C. Nowak, Tiago Medeiros-Furquim, Tegan A. Otto, Sam W. Lee, Randolph J. Noelle, Bart J. L. Eggen and Jon D. Laman

    Citation: Acta Neuropathologica Communications 2021 9:91

    Content type: Research

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  15. Tauopathies are a group of neurodegenerative diseases characterized by the alteration/aggregation of TAU protein, for which there is still no effective treatment. Therefore, new pharmacological targets are bei...

    Authors: M. Galán-Ganga, C. Rodríguez-Cueto, J. Merchán-Rubira, F. Hernández, J. Ávila, M. Posada-Ayala, J. L. Lanciego, E. Luengo, M. G. Lopez, A. Rábano, J. Fernández-Ruiz and I. Lastres-Becker

    Citation: Acta Neuropathologica Communications 2021 9:90

    Content type: Research

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  16. Traumatic brain injury (TBI) causes chronic symptoms and increased risk of neurodegeneration. Axons in white matter tracts, such as the corpus callosum (CC), are critical components of neural circuits and part...

    Authors: Donald V. Bradshaw Jr., Andrew K. Knutsen, Alexandru Korotcov, Genevieve M. Sullivan, Kryslaine L. Radomski, Bernard J. Dardzinski, Xiaomei Zi, Dennis P. McDaniel and Regina C. Armstrong

    Citation: Acta Neuropathologica Communications 2021 9:89

    Content type: Research

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  17. Diffuse intrinsic pontine glioma (DIPG), a rare pediatric brain tumor, afflicts approximately 350 new patients each year in the United States. DIPG is noted for its lethality, as fewer than 1% of patients surv...

    Authors: Xiaolei Lian, Dina Kats, Samuel Rasmussen, Leah R. Martin, Anju Karki, Charles Keller and Noah E. Berlow

    Citation: Acta Neuropathologica Communications 2021 9:88

    Content type: Research

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    The Correction to this article has been published in Acta Neuropathologica Communications 2021 9:114

  18. In neurodegenerative diseases including Alzheimer’s, Parkinson’s and prion diseases, astrocytes acquire disease-associated reactive phenotypes. With growing appreciation of their role in chronic neurodegenerat...

    Authors: Natallia Makarava, Olga Mychko, Jennifer Chen-Yu Chang, Kara Molesworth and Ilia V. Baskakov

    Citation: Acta Neuropathologica Communications 2021 9:87

    Content type: Research

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  19. Chronic traumatic encephalopathy (CTE) is a progressive neurodegenerative disease, characterized by hyperphosphorylated tau, found in individuals with a history of exposure to repetitive head impacts. While th...

    Authors: Jonathan D. Cherry, Camille D. Esnault, Zachary H. Baucom, Yorghos Tripodis, Bertrand R. Huber, Victor E. Alvarez, Thor D. Stein, Dennis W. Dickson and Ann C. McKee

    Citation: Acta Neuropathologica Communications 2021 9:86

    Content type: Research

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  20. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Marangelie Criado-Marrero, Niat T. Gebru, Danielle M. Blazier, Lauren A. Gould, Jeremy D. Baker, David Beaulieu-Abdelahad and Laura J. Blair

    Citation: Acta Neuropathologica Communications 2021 9:85

    Content type: Correction

    Published on:

    The original article was published in Acta Neuropathologica Communications 2021 9:65

  21. Defective amyloid-β (Aβ) clearance from the brain is a major contributing factor to the pathophysiology of Alzheimer’s disease (AD). Aβ clearance is mediated by macrophages, enzymatic degradation, perivascular...

    Authors: Xiao Zhang, Paul O’Callaghan, Honglian Li, Yingxia Tan, Ganlin Zhang, Uri Barash, Xiaomin Wang, Lars Lannfelt, Israel Vlodavsky, Ulf Lindahl and Jin-Ping Li

    Citation: Acta Neuropathologica Communications 2021 9:84

    Content type: Research

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  22. When injected into genetically modified mice, aggregates of the amyloid-β (Aβ) peptide from the brains of Alzheimer’s disease (AD) patients or transgenic AD mouse models seed cerebral Aβ deposition in a prion-...

    Authors: Alejandro Ruiz-Riquelme, Alison Mao, Marim M. Barghash, Heather H. C. Lau, Erica Stuart, Gabor G. Kovacs, K. Peter R. Nilsson, Paul E. Fraser, Gerold Schmitt-Ulms and Joel C. Watts

    Citation: Acta Neuropathologica Communications 2021 9:83

    Content type: Research

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  23. Chorea-Acanthocytosis (ChAc) is a devastating, little understood, and currently untreatable neurodegenerative disease caused by VPS13A mutations. Based on our recent demonstration that accumulation of activated L...

    Authors: Kevin Peikert, Enrica Federti, Alessandro Matte, Gabriela Constantin, Enrica Caterina Pietronigro, Paolo Francesco Fabene, Paola Defilippi, Emilia Turco, Federico Del Gallo, Pietro Pucci, Angela Amoresano, Anna Illiano, Flora Cozzolino, Maria Monti, Francesca Garello, Enzo Terreno…

    Citation: Acta Neuropathologica Communications 2021 9:81

    Content type: Research

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  24. Multiple system atrophy (MSA) is an insidious middle age-onset neurodegenerative disease that clinically presents with variable degrees of parkinsonism and cerebellar ataxia. The pathological hallmark of MSA i...

    Authors: Ethan W. Hass, Zachary A. Sorrentino, Grace M. Lloyd, Nikolaus R. McFarland, Stefan Prokop and Benoit I. Giasson

    Citation: Acta Neuropathologica Communications 2021 9:80

    Content type: Research

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  25. The MYH2 gene encodes the skeletal muscle myosin heavy chain IIA (MyHC-IIA) isoform, which is expressed in the fast twitch type 2A fibers. Autosomal dominant or recessive pathogenic variants in MYH2 lead to conge...

    Authors: Nicolas N. Madigan, Michael J. Polzin, Gaofeng Cui, Teerin Liewluck, Mohammad H. Alsharabati, Christopher J. Klein, Anthony J. Windebank, Georges Mer and Margherita Milone

    Citation: Acta Neuropathologica Communications 2021 9:79

    Content type: Case report

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  26. Alzheimer’s disease (AD) is the most common cause of age-related dementia. Increasing evidence suggests that neuroinflammation mediated by microglia and astrocytes contributes to disease progression and severi...

    Authors: Jong-Sung Park, Tae-In Kam, Saebom Lee, Hyejin Park, Yumin Oh, Seung-Hwan Kwon, Jae-Jin Song, Donghoon Kim, Hyunhee Kim, Aanishaa Jhaldiyal, Dong Hee Na, Kang Choon Lee, Eun Ji Park, Martin G. Pomper, Olga Pletnikova, Juan C. Troncoso…

    Citation: Acta Neuropathologica Communications 2021 9:78

    Content type: Research

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  27. Sex is an important factor that contributes to the clinical and biological heterogeneities in Alzheimer’s disease (AD), but the regulatory mechanisms underlying sex disparity in AD are still not well understoo...

    Authors: Lanyu Zhang, Juan I. Young, Lissette Gomez, Tiago C. Silva, Michael A. Schmidt, Jesse Cai, Xi Chen, Eden R. Martin and Lily Wang

    Citation: Acta Neuropathologica Communications 2021 9:77

    Content type: Research

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  28. Post-traumatic epilepsy (PTE) accounts for 5% of all epilepsies and 10–20% of the acquired forms. The latency between traumatic brain injury (TBI) and epilepsy onset in high-risk patients offers a therapeutic ...

    Authors: Rossella Di Sapia, Federico Moro, Marica Montanarella, Valentina Iori, Edoardo Micotti, Daniele Tolomeo, Kevin K. W. Wang, Annamaria Vezzani, Teresa Ravizza and Elisa R. Zanier

    Citation: Acta Neuropathologica Communications 2021 9:76

    Content type: Research

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  29. Age at onset of amyotrophic lateral sclerosis (ALS) is highly variable (eg, 27–74 years in carriers of the G4C2-expansion in C9orf72). It might be influenced by environmental and genetic factors via the modulatio...

    Authors: Ming Zhang, Zhengrui Xi, Sara Saez-Atienzar, Ruth Chia, Danielle Moreno, Christine Sato, Mahdi Montazer Haghighi, Bryan J. Traynor, Lorne Zinman and Ekaterina Rogaeva

    Citation: Acta Neuropathologica Communications 2021 9:75

    Content type: Research

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  30. Traumatic brain injury (TBI) is considered as the most robust environmental risk factor for Alzheimer’s disease (AD). Besides direct neuronal injury and neuroinflammation, vascular impairment is also a hallmar...

    Authors: Yingxi Wu, Haijian Wu, Jianxiong Zeng, Brock Pluimer, Shirley Dong, Xiaochun Xie, Xinying Guo, Tenghuan Ge, Xinyan Liang, Sudi Feng, Youzhen Yan, Jian-Fu Chen, Naomi Sta Maria, Qingyi Ma, Fernando Gomez-Pinilla and Zhen Zhao

    Citation: Acta Neuropathologica Communications 2021 9:74

    Content type: Research

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  31. Transcribed nucleotide repeat expansions form detectable RNA foci in patient cells that contribute to disease pathogenesis. The most widely used method for detecting RNA foci, fluorescence in situ hybridizatio...

    Authors: M. Rebecca Glineburg, Yuan Zhang, Amy Krans, Elizabeth M. Tank, Sami J. Barmada and Peter K. Todd

    Citation: Acta Neuropathologica Communications 2021 9:73

    Content type: Research

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  32. Traumatic brain injury (TBI) can result in progressive cognitive decline occurring for years after the initial insult, and for which there is currently no pharmacological treatment. An ongoing chronic inflamma...

    Authors: Khalil Mallah, Christine Couch, Mohammed Alshareef, Davis Borucki, Xiaofeng Yang, Ali Alawieh and Stephen Tomlinson

    Citation: Acta Neuropathologica Communications 2021 9:72

    Content type: Research

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  33. Insulin is an important hormone for brain function, and alterations in insulin metabolism may be associated with neuropathology. We examined associations of molecular markers of brain insulin signaling with ce...

    Authors: Zoe Arvanitakis, Ana W. Capuano, Hoau-Yan Wang, Julie A. Schneider, Alifiya Kapasi, David A. Bennett, Rexford S. Ahima and Steven E. Arnold

    Citation: Acta Neuropathologica Communications 2021 9:71

    Content type: Research

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  34. Huntington’s disease (HD) is a late onset, inherited neurodegenerative disorder for which early pathogenic events remain poorly understood. Here we show that mutant exon 1 HTT proteins are recruited to a subse...

    Authors: Ya Zhou, Thomas R. Peskett, Christian Landles, John B. Warner, Kirupa Sathasivam, Edward J. Smith, Shu Chen, Ronald Wetzel, Hilal A. Lashuel, Gillian P. Bates and Helen R. Saibil

    Citation: Acta Neuropathologica Communications 2021 9:70

    Content type: Research

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  35. Prognostic molecular subgrouping of glioblastoma is an ongoing effort and the current classification includes IDH-wild-type and IDH-mutant entities, the latter showing significantly better prognosis. We perfor...

    Authors: Maria-Magdalena Georgescu, Mohammad Zahidul Islam, Yan Li, James Traylor and Anil Nanda

    Citation: Acta Neuropathologica Communications 2021 9:69

    Content type: Research

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  36. Multiple system atrophy (MSA) is a rare, but fatal atypical parkinsonian disorder. The prototypical pathological hallmark are oligodendroglial cytoplasmic inclusions (GCIs) containing alpha-synuclein (α-syn). ...

    Authors: Lisa Mészáros, Markus J. Riemenschneider, Heiko Gassner, Franz Marxreiter, Stephan von Hörsten, Alana Hoffmann and Jürgen Winkler

    Citation: Acta Neuropathologica Communications 2021 9:68

    Content type: Research

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  37. One of the most prominent features of glioblastoma (GBM) is hyper-vascularization. Bone marrow-derived macrophages are actively recruited to the tumor and referred to as glioma-associated macrophages (GAMs) wh...

    Authors: Qingxia Wei, Olivia Singh, Can Ekinci, Jaspreet Gill, Mira Li, Yasin Mamatjan, Shirin Karimi, Severa Bunda, Sheila Mansouri, Kenneth Aldape and Gelareh Zadeh

    Citation: Acta Neuropathologica Communications 2021 9:67

    Content type: Research

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  38. The amyloid precursor protein (APP) is a type I transmembrane protein with unknown physiological function but potential impact in neurodegeneration. The current study demonstrates that APP signals to the nucle...

    Authors: David Marks, Natalie Heinen, Lisa Bachmann, Sophia Meermeyer, Michelle Werner, Lucia Gallego, Peter Hemmerich, Verian Bader, Konstanze F. Winklhofer, Elisabeth Schröder, Shirley K. Knauer and Thorsten Müller

    Citation: Acta Neuropathologica Communications 2021 9:66

    Content type: Research

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  39. The microtubule associated protein tau is an intrinsically disordered phosphoprotein that accumulates under pathological conditions leading to formation of neurofibrillary tangles, a hallmark of Alzheimer’s di...

    Authors: Marangelie Criado-Marrero, Niat T. Gebru, Danielle M. Blazier, Lauren A. Gould, Jeremy D. Baker, David Beaulieu-Abdelahad and Laura J. Blair

    Citation: Acta Neuropathologica Communications 2021 9:65

    Content type: Research

    Published on:

    The Correction to this article has been published in Acta Neuropathologica Communications 2021 9:85

  40. Protein misfolding diseases refer to a variety of disorders that develop as a consequence of the misfolding of proteins in various organs. The etiologies of Parkinson’s and Alzheimer’s disease remain unclear, ...

    Authors: Ivan Martinez-Valbuena, Rafael Valenti-Azcarate, Irene Amat-Villegas, Irene Marcilla, Gloria Marti-Andres, Maria-Cristina Caballero, Mario Riverol, María-Teresa Tuñon, Paul E. Fraser and María-Rosario Luquin

    Citation: Acta Neuropathologica Communications 2021 9:64

    Content type: Research

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  41. Traumatic brain injury (TBI) is a major cause of long-term disability in young adults. An evidence-based treatment for TBI recovery, especially in the chronic phase, is not yet available. Using a severe TBI mo...

    Authors: Xuecheng Qiu, Suning Ping, Michele Kyle, Lawrence Chin and Li-Ru Zhao

    Citation: Acta Neuropathologica Communications 2021 9:63

    Content type: Research

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  42. Definitive diagnosis of Parkinson’s disease (PD) and dementia with Lewy bodies (DLB) relies on postmortem finding of disease-associated alpha-synuclein (αSynD) as misfolded protein aggregates in the central nervo...

    Authors: Connor Bargar, Wen Wang, Steven A. Gunzler, Alexandra LeFevre, Zerui Wang, Alan J. Lerner, Neena Singh, Curtis Tatsuoka, Brian Appleby, Xiongwei Zhu, Rong Xu, Vahram Haroutunian, Wen-Quan Zou, Jiyan Ma and Shu G. Chen

    Citation: Acta Neuropathologica Communications 2021 9:62

    Content type: Methodology article

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  43. Retinoblastoma is a childhood cancer of the retina involving germline or somatic alterations of the RB Transcriptional Corepressor 1 gene, RB1. Rare cases of sellar-suprasellar region retinoblastoma without evide...

    Authors: Kathleen M. Schieffer, Alexander Z. Feldman, Esko A. Kautto, Sean McGrath, Anthony R. Miller, Maria Elena Hernandez-Gonzalez, Stephanie LaHaye, Katherine E. Miller, Daniel C. Koboldt, Patrick Brennan, Benjamin Kelly, Amy Wetzel, Vibhuti Agarwal, Margaret Shatara, Suzanne Conley, Diana P. Rodriguez…

    Citation: Acta Neuropathologica Communications 2021 9:61

    Content type: Case report

    Published on:

  44. We have previously reported long-term changes in the brains of non-concussed varsity rugby players using magnetic resonance spectroscopy (MRS), diffusion tensor imaging (DTI) and functional magnetic imaging (f...

    Authors: Xiaoyun Xu, Matthew Cowan, Flavio Beraldo, Amy Schranz, Patrick McCunn, Nicole Geremia, Zalman Brown, Maitray Patel, Karen L. Nygard, Reza Khazaee, Lihong Lu, Xingyu Liu, Michael J. Strong, Gregory A. Dekaban, Ravi Menon, Robert Bartha…

    Citation: Acta Neuropathologica Communications 2021 9:60

    Content type: Research

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  45. Short survival of glioblastoma (GBM) patients is due to systematic tumor recurrence. Our laboratory identified a GBM cell subpopulation able to leave the tumor mass (TM) and invade the subventricular zone (SVZ...

    Authors: Marina Digregorio, Natacha Coppieters, Arnaud Lombard, Paul Noel Lumapat, Felix Scholtes and Bernard Rogister

    Citation: Acta Neuropathologica Communications 2021 9:59

    Content type: Research

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  46. Prion diseases are fatal, infectious, and incurable neurodegenerative disorders caused by misfolding of the cellular prion protein (PrPC) into the infectious isoform (PrPSc). In humans, there are sporadic, geneti...

    Authors: Tahir Ali, Samia Hannaoui, Satish Nemani, Waqas Tahir, Irina Zemlyankina, Pearl Cherry, Su Yeon Shim, Valerie Sim, Hermann M. Schaetzl and Sabine Gilch

    Citation: Acta Neuropathologica Communications 2021 9:58

    Content type: Research

    Published on:

  47. Frontotemporal lobar degeneration (FTLD) causes a spectrum of clinical presentations of frontotemporal dementia (FTD), including progressive changes in behavior, personality, executive function, and language. ...

    Authors: Jonathan Frew and Haakon Berge Nygaard

    Citation: Acta Neuropathologica Communications 2021 9:57

    Content type: Research

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  48. Amyloid-β (Aβ) misfolding is one of the hallmark pathological features of Alzheimer’s disease (AD). AD can manifest with diverse symptomatology including variable rates of cognitive decline, duration of clinic...

    Authors: Claudia Duran-Aniotz, Ines Moreno-Gonzalez, Nazaret Gamez, Nelson Perez-Urrutia, Laura Vegas-Gomez,, Claudio Soto and Rodrigo Morales

    Citation: Acta Neuropathologica Communications 2021 9:56

    Content type: Research

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