Fig. 6
From: Retina-to-brain spreading of α-synuclein after intravitreal injection of preformed fibrils
Microgliosis in the optic nerve of PFF-injected mice. A Representative images of Iba-1 immunoreactivity in the optic nerve 1, 2, and 5 months after injection. B–D Quantification of Iba-1 immunoreactivity in the optic nerve. Scale bar: 50 µm. Data are expressed as means ± s.e.m, relative to control (PBS, n = 5; PFF, n = 5; *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.000; Student’s t-test)