Fig. 4

Tumor neoantigens and cellular Characterization of Immune Infiltrates in Solid Cancers. A Tumor mutational burden (TMB), neoantigen load and Long-rank survival analysis based on a high and low amount of neoantigens in each tumor from TCGA cohort. B, C Correlation between neoantigen load and the TBM (B) or p value of survival analysis (C) in each tumor. D Percentage of CD8 positive T cells, regulatory T cells, Macrophague M1, Macrophague M2, CD4 positive T cells and monocyte populations on total CD45 suspension in each type of tumor from the TCGA cohort. E Correlation between neoantigen load and CD8 positive T cells in each tumor. F–H, Correlation between CD8 positive T cells and myeloid cells (F), macrophages M2 cells (G) and the ratio of M2/M1 cells (H) in each tumor from TCGA cohort