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Fig. 3 | Acta Neuropathologica Communications

Fig. 3

From: Late chronic local inflammation, synaptic alterations, vascular remodeling and arteriovenous malformations in the brains of male rats exposed to repetitive low-level blast overpressures

Fig. 3

Periarterial apoptotic microglia and astrocytes. a and b show a cerebral artery (identified by its longitudinal and transverse smooth muscle nuclei) surrounded by a patch of activated microglia and stained with TUNEL. Microglia (Iba1, white), astrocytes (GFAP, red), and nuclei (DAPI, blue). Note the presence of apoptotic bodies (green, arrows) in activated unramified microglia and perivascular astrocytes. c, Electron microscopy of an activated microglial cell within an enlarged paravascular space (asterisks) and harboring secondary lysosomes and residual bodies (arrows). Scale, 30 µm in a and b, and 1 µm in c

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Acta Neuropathologica Communications

ISSN: 2051-5960

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