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Fig. 17 | Acta Neuropathologica Communications

Fig. 17

From: Late chronic local inflammation, synaptic alterations, vascular remodeling and arteriovenous malformations in the brains of male rats exposed to repetitive low-level blast overpressures

Fig. 17

X-ray micro-CT scan showing blast-induced arteriovenous malformations. a-f, two serial optical coronal sections (1.5 mm-thick) of a BriteVu-perfused brain are shown, along with additional sections in Figs. 15 and 16. a-c, Interaural 9.84–8.34 mm; d-f, interaural 8.34–6.84 mm. Arrows in a-b and d-e denote the formation of arteriovenous malformations within the tear-damaged insular cortex. Arrowheads in a and c indicate a small area with much lower X-ray attenuation than the surrounding tissue, consistent with an air void within the tissue when compared to the surrounding areas. This region maps to the damaged lateral ventricle with a tear extending through the corpus callosum and into the motor cortex (Fig. 15). Arrowheads in d and f indicate an artery with high tortuosity in the rostral hippocampus. Scale, 1 mm in a and d; 2.2 mm in b and e; 0.3 mm in c and f

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